BAKER BROS. ADVISORS LP

NEW YORK, NY Investment Advisor Hedge Fund Activist Investor
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Baker Bros. Advisors is based out of New York. Baker Bros. Advisors is a hedge fund with 2 clients and discretionary assets under management (AUM) of $23,154,517,129 (Form ADV from 2023-03-24). Their last reported 13F filing for Q2 2023 included $17,279,240,811 in managed 13F securities and a top 10 holdings concentration of 87.61%. Baker Bros. Advisors's largest holding is Seagen Inc with shares held of 44,554,162. Baker Bros. Advisors has met the qualifications for inclusion in our WhaleScore system. Whalewisdom has at least 87 13F filings, 176 13D filings, 244 13G filings, and 147 Form 4 filings

06/30/2023

13F Activity

  • Market Value $17.279 Billion
  • Prior Market Value $18.38 Billion
  • New Purchases7 stocks
  • Additional Purchases21 stocks
  • Sold out of5 stocks
  • Reduced holdings in12 stocks
  • Top 10 Holdings % 87.61 %
  • Turnover % [1]:11.22%
  • Turnover Alt % [2]: 2.31 %
  • Time Held Top20:18.00 quarters
  • Time Held Top10:23.00 quarters
  • Time Held All:13.27 quarters

[1]: Turnover is calculated by taking the # of new holdings (initial purchases) + the # of positions sold out of (not just reduced) divided by the total # of holdings for the quarter.

[2]: Alt Turnover is calculated by taking either the total MV of new purchases or the MV of securities sold, whichever is less, divided by the total MV of the fund.

06/30/2023

13F Sector Allocation Over Time

Fund Metrics

You are limited to the prior 8 quarters of 13F filings. Subscribe to WhaleWisdom to view all filing data for BAKER BROS. ADVISORS LP

Portfolio Analysis

Classifications:

Q2 2023:

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Consistent Across Past 12 Quarters:

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Type of 13F Disclosure 13F Holdings Report
% of holdings ETF 0.0
% of top 20 holdings the same as top 20 most commonly held by all managers 0.0%
ALL HOLDINGS TOP-20 HOLDINGS
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Sector Allocation 0.111% ( ) 99.889% (HEALTH CARE) 50.0% 50.0% 100.0% (HEALTH CARE) 100.0% (HEALTH CARE) 100.0% 100.0%

Risk/Reward Analysis

Portfolio Market Cap Analysis

Portfolio Performance

Top 20 equal-weighted holdings. Performance numbers calculated through 2023-08-14

Performance for Q2 2023: -3.74%
Performance Last 4 Quarters: 6.02%
Performance Metrics
Stdev (5-yrs): Subscription required BETA (5-yrs): Subscription required ALPHA (3-yrs): Subscription required
Max Drawdown (all-years): Subscription required Annualized Perf (3-yrs): Subscription required Batting Avg vs S&P. (3-yrs): Subscription required
Sortino (3-yrs): Subscription required Stutzer (3-yrs): Subscription required Treynor (3-yrs): Subscription required
Sterling (3-yrs): Subscription required Calmar (3-yrs): Subscription required Information Ratio (3-yrs): Subscription required
Tracking Error (3 yrs): Subscription required Stdev Down (3-yrs): Subscription required Winning Months %: Subscription required
Losing Months %: Subscription required Best 12 Months: Subscription required Worst 12 Months: Subscription required
Efficiency Ratio (3-yrs): Subscription required Sharpe: Subscription required Stdev Sectors: Subscription required
Skewness (3-yrs): Subscription required Kurtosis (3-yrs): Subscription required Upside Potential (3-yrs): Subscription required

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*Shares are split adjusted

Global (ex. US) Holdings

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Stale Holdings (no activity in past 21-months or sold out)

Source: Refinitiv. Stale holdings data removed after 21-months of inactivity.

View Last Form Adv Compilation Report on Record

BAKER BROTHERS INVESTMENTS
Classified as Hedge Fund
860 WASHINGTON STREET, 3RD FLOOR
NEW YORK NY    10014
Country: United States

Business Phone: 212-339-5600
Fax: 212-339-5688
Professional Investment Advisor Data
SEC Registration as : Large Advisory Firm
Form of Organization: Limited Partnership
Organized in: DE
Number of employees: 50
Other Business Activities:
Advisor Fees/Compensation: Percentage of assets under management,Performance-based fees
Amount of client funds and securities: 0
Total Number of Clients: 2
Amount of client funds and securities by related persons: 23,154,500,000
Total Number of clients from related persons: 2
Disclosures:
Data above was derived from SEC filings.

Active Schedule 13D and 13G events

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Insider Transactions in the past year

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BAKER BROS. ADVISORS LP

ownership team - last updated 2023-03-24
Name Title Start Date Direct/Indirect % Ownership
BAKER, JULIAN, CHARLES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER BROS. ADVISORS (GP), LLC GENERAL PARTNER 01/01/2000 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS LP GENERAL PARTNER direct 2000-01-01
LESSING, SCOTT, LAWRENCE PRESIDENT, CHIEF COMPLIANCE OFFICER 02/01/2011 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC PRESIDENT, CHIEF COMPLIANCE OFFICER direct 2011-02-01
TOOHEY, ALEXANDRA, ANN CHIEF FINANCIAL OFFICER 01/01/2014 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
ATTARA CAPITAL LP CHIEF EXECUTIVE OFFICER direct 2009-12-01
BAKER BROS. ADVISORS LP CHIEF FINANCIAL OFFICER direct 2014-01-01
BAKER, FELIX, JAMES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, JULIAN, CHARLES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, FELIX, JAMES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01

Private Funds

Name Country Fund Identification Number Fund Type Gross Asset Value Minimum Investment Other
BAKER BROTHERS LIFE SCIENCES, L.P. United States 805-9378432489 Hedge Fund 21,301,033,217 40,000,000 Master Fund
667, L.P. United States 805-7902319250 Hedge Fund 1,853,483,912 40,000,000

BAKER BROS. ADVISORS LP

ownership team - last updated 2022-03-28
Name Title Start Date Direct/Indirect % Ownership
BAKER, JULIAN, CHARLES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER BROS. ADVISORS (GP), LLC GENERAL PARTNER 01/01/2000 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS LP GENERAL PARTNER direct 2000-01-01
LESSING, SCOTT, LAWRENCE PRESIDENT, CHIEF COMPLIANCE OFFICER 02/01/2011 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC PRESIDENT, CHIEF COMPLIANCE OFFICER direct 2011-02-01
TOOHEY, ALEXANDRA, ANN CHIEF FINANCIAL OFFICER 01/01/2014 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
ATTARA CAPITAL LP CHIEF EXECUTIVE OFFICER direct 2009-12-01
BAKER BROS. ADVISORS LP CHIEF FINANCIAL OFFICER direct 2014-01-01
BAKER, FELIX, JAMES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, JULIAN, CHARLES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, FELIX, JAMES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01

Private Funds

Name Country Fund Identification Number Fund Type Gross Asset Value Minimum Investment Other
BAKER BROTHERS LIFE SCIENCES, L.P. United States 805-9378432489 Hedge Fund 23,423,422,192 40,000,000 Master Fund
667, L.P. United States 805-7902319250 Hedge Fund 2,266,121,438 40,000,000

BAKER BROS. ADVISORS LP

ownership team - last updated 2021-03-30
Name Title Start Date Direct/Indirect % Ownership
BAKER, JULIAN, CHARLES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER BROS. ADVISORS (GP), LLC GENERAL PARTNER 01/01/2000 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS LP GENERAL PARTNER direct 2000-01-01
LESSING, SCOTT, LAWRENCE PRESIDENT, CHIEF COMPLIANCE OFFICER 02/01/2011 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC PRESIDENT, CHIEF COMPLIANCE OFFICER direct 2011-02-01
TOOHEY, ALEXANDRA, ANN CHIEF FINANCIAL OFFICER 01/01/2014 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
ATTARA CAPITAL LP CHIEF EXECUTIVE OFFICER direct 2009-12-01
BAKER BROS. ADVISORS LP CHIEF FINANCIAL OFFICER direct 2014-01-01
BAKER, FELIX, JAMES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, JULIAN, CHARLES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, FELIX, JAMES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01

Private Funds

Name Country Fund Identification Number Fund Type Gross Asset Value Minimum Investment Other
BAKER BROTHERS LIFE SCIENCES, L.P. United States 805-9378432489 Hedge Fund 32,797,596,057 40,000,000 Master Fund
667, L.P. United States 805-7902319250 Hedge Fund 2,974,776,160 40,000,000

BAKER BROS. ADVISORS LP

ownership team - last updated 2020-03-25
Name Title Start Date Direct/Indirect % Ownership

Private Funds

Name Country Fund Identification Number Fund Type Gross Asset Value Minimum Investment Other
BAKER BROTHERS LIFE SCIENCES, L.P. United States 805-9378432489 Hedge Fund 21,642,241,082 40,000,000 Master Fund
14159, L.P. United States 805-9816274483 Hedge Fund 16,954,418 40,000,000
667, L.P. United States 805-7902319250 Hedge Fund 1,898,783,573 40,000,000

BAKER BROS. ADVISORS LP

ownership team - last updated 2019-03-18
Name Title Start Date Direct/Indirect % Ownership
BAKER, JULIAN, CHARLES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER BROS. ADVISORS (GP), LLC GENERAL PARTNER 01/01/2000 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS LP GENERAL PARTNER direct 2000-01-01
LESSING, SCOTT, LAWRENCE PRESIDENT, CHIEF COMPLIANCE OFFICER 02/01/2011 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC PRESIDENT, CHIEF COMPLIANCE OFFICER direct 2011-02-01
TOOHEY, ALEXANDRA, ANN CHIEF FINANCIAL OFFICER 01/01/2014 Direct less than 5%
max of 20 shown
Fund Name Position direct/indirect start date end date
ATTARA CAPITAL LP CHIEF EXECUTIVE OFFICER direct 2009-12-01
BAKER BROS. ADVISORS LP CHIEF FINANCIAL OFFICER direct 2014-01-01
BAKER, FELIX, JAMES LIMITED PARTNER 01/01/2000 Direct 25 - 50%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, JULIAN, CHARLES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01
BAKER, FELIX, JAMES MANAGING MEMBER BAKER BROS. ADVISORS (GP), LLC 01/01/2000 Indirect 50 - 75%
max of 20 shown
Fund Name Position direct/indirect start date end date
BAKER BROS. ADVISORS, LLC CO-MANAGING MEMBER direct 2000-01-01
BAKER BROS. ADVISORS LP MEMBER indirect 2000-01-01

Private Funds

Name Country Fund Identification Number Fund Type Gross Asset Value Minimum Investment Other
BAKER BROS. INVESTMENTS II, L.P. United States 805-8976652096 Hedge Fund 1,217,800 40,000,000
BAKER BROS. INVESTMENTS, L.P. United States 805-6854596471 Hedge Fund 9,815,602 40,000,000
BAKER BROTHERS LIFE SCIENCES, L.P. United States 805-9378432489 Hedge Fund 15,727,945,892 40,000,000 Master Fund
14159, L.P. United States 805-9816274483 Hedge Fund 64,063,878 40,000,000
BAKER/TISCH INVESTMENTS L.P. United States 805-3184499373 Hedge Fund 10,957,210 40,000,000
667, L.P. United States 805-7902319250 Hedge Fund 1,504,095,439 40,000,000

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