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SARISSA CAPITAL MANAGEMENT LP
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GREENWICH CT
Investment Advisor
Hedge Fund
Activist Investor
Sarissa Capital Management is based out of Greenwich and is run by Alex Denner. Sarissa Capital Management is a hedge fund with 10 clients and discretionary assets under management (AUM) of $926,987,169 (Form ADV from 2024-03-29). Their last reported 13F filing for Q4 2024 included $322,862,731 in managed 13F securities
and a top 10 holdings concentration of 100.0%. Sarissa Capital Management's largest holding is Innoviva Inc with shares held of 7,277,000. Whalewisdom has at least 46 13F filings, 87 13D filings, and 3 13G filings
Business Description
Sarissa Capital Management LP (“Sarissa” or the “Firm”) is a Delaware limited partnership formed in January of 2013. Sarissa is led by Alexander Denner, Ph.D. and a dedicated team of investment and operations professionals. Dr. Denner ultimately controls Sarissa through its general partner, Sarissa Capital Management GP LLC (the “Firm GP”). Dr. Denner is the principal owner of Sarissa and the Firm GP.
Sarissa provides discretionary advisory services to pooled investment vehicles (each a “Fund” and collectively the “Funds”) and a separately managed account (the “SMA”). Generally, Sarissa trades the Funds’ or SMA’s assets but will in certain limited instances direct an outsourced trader to execute transactions. Sarissa or its affiliates may cause the Advisory Clients, either alone or together with others, to acquire a “control” position in any company and may secure the appointment of persons to such company’s management team or board of directors.
Investment Strategy
Sarissa may offer any advisory services, engage in any investment strategy, and make any investment that it considers appropriate, subject to each Advisory Client’s investment objectives and guidelines. The investment strategies that Sarissa pursues are speculative and entail substantial risks.
The Hawkeye Fund and Master Fund II follow investment programs substantially similar to that of the Master Fund with respect to long only trades and generally participates in investments alongside the Master Fund on a pro rata basis. The Hawkeye fund and Master Fund II do not undertake any short trades.
Owners
- SARISSA CAPITAL MANAGEMENT GP LLC - GENERAL PARTNER
- DENNER, ALEXANDER, JOHN - CHIEF EXECUTIVE OFFICER/CHIEF INVESTMENT OFFICER
- DIPAOLO, MARK, ANTHONY - CHIEF LEGAL OFFICER/GENERAL COUNSEL
- BONFIGLIO, PATRICE, EADON - CHIEF COMPLIANCE OFFICER Click on the Ownership/Private Fund Data tab for more details.
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2024-12-31
Top Buys (13F)
Name | % Change |
---|---|
LNTH Lantheus Holdings In | 1.04% |

2024-12-31
Top Sells (13F)
Name | % Change |
---|---|
GILD Gilead Sciences Inc | 8.41% |
CYTK Cytokinetics Inc | 2.42% |
BIIB Biogen Inc | 1.3% |
RGLS Regulus Therapeutics | 0.07% |

2024-12-31
13F Holdings Summary
Name | $ Change |
---|---|
INVA Innoviva Inc | 39.11% |
IRWD Ironwood Pharmaceuti | 22.49% |
NBIX Neurocrine Bioscienc | 13.07% |
CYTK Cytokinetics Inc | 12.15% |
GILD Gilead Sciences Inc | 7.5% |

2024-12-31
13F Activity
Market Value | $323m, Prior: $402m |
Inflows (Outflows) as % of Total MV | (-22.9959)% |
New Purchases | 0 stocks |
Added To | 1 stocks |
Sold out of | 2 stocks |
Reduced holdings in | 3 stocks |
Top 10 Holdings % | 100% |
Turnover %[1] | 20% |
Turnover Alt %[2] | 1.03% |
Time Held Top 20 | 14.25 quarters |
Time Held Top 10 | 14.25 quarters |
Time Held All | 14.25 quarters |
[1]: Turnover is calculated by taking the # of new holdings (initial purchases) + the # of positions sold out of (not just reduced) divided by the total # of holdings for the quarter.
[2]: Alt Turnover is calculated by taking either the total MV of new purchases or the MV of securities sold, whichever is less, divided by the total MV of the fund.

2024-12-31
13F Sector Allocation Over Time
limited to past 4 quarters. Subscribe to see all available data

2024-12-31
Analysis

Top 20 equal-weighted holdings. Performance numbers calculated through 2024-12-31