Form Type: 4

Accession Number:	0001127602-20-009831
Date:	2020-03-04
Issuer:	AVROBIO, INC. (AVRO)
Original Submission Date:

Reporting Person:

MACKAY GEOFFREY
C/O AVROBIO, INC.
ONE KENDALL SQUARE, BLDG. 300, SUITE 201 CAMBRIDGE, MA 02139

Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
Title of Security	Transaction Date	2a. Deemed Execution Date	Transaction Code	Shares	Acquired or Disposed	Price per share	5. Amount of Securities Beneficially Owned Following Reported Transaction	6. Ownership Form Direct or Indirect	Nature of Indirect Ownership

Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, convertible securities
Title of Derivative Security	Conversion or Exercise Price of Derivative Security	Transaction Date	Deemed Execution Date	Transaction Code	Number of Derivative Securities Acquired (A) or Disposed of (D)	Date Exercisable	Expiration Date	Title and Amount of Securities Underlying Derivative Security	Price of Derivative Security	Number of derivative Securities Beneficially Owned Following Reported Transaction(s)	Ownership Form: Direct (D) or Indirect (I)	Nature of Indirect Beneficial Ownership
STOCK OPTION (RIGHT TO BUY)	21.44	2020-03-04	deemed execution date	A	292,300 (a)		2030-03-03	common stock 292,300	$21.44	292,300	direct

Footnotes
ID	footnote
f1	25% of the shares shall vest and become exercisable on march 4, 2021, and the remaining 75% shall vest in equal monthly installments thereafter over a 3 year period.

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