f2 |
these shares of the issuer's common stock are held of record by orbimed private investments vi, lp ("opi vi"). orbimed capital gp vi llc ("gp vi") is the general partner of opi vi, and orbimed advisors llc ("orbimed advisors"), a registered investment adviser under the investment advisors act of 1940, as amended, is the managing member of gp vi. by virtue of such relationships, gp vi and orbimed advisors may be deemed to have voting and investment power with respect to the securities held by opi vi noted above and as a result may be deemed to beneficially own such securities for purposes of rule 13d-3 under the securities exchange act of 1934, as amended (the "exchange act"). orbimed advisors exercises this investment and voting power through a management committee comprised of carl l. gordon, sven h. borho, and jonathan t. silverstein, each of whom disclaims beneficial ownership of the shares held by opi vi. |
f3 |
this report on form 4 is jointly filed by gp vi and orbimed advisors. each of the reporting persons disclaims beneficial ownership of the securities reported herein for purposes of rule 16a-1(a) under the exchange act, except to the extent of its pecuniary interest therein, if any. the reporting persons have designated a representative, currently chau khuong ("khuong"), an employee of orbimed advisors, to serve on the issuer's board of directors. this report shall not be deemed an admission that any of the reporting persons or khuong is a beneficial owner of such securities for the purposes of section 16 of the exchange act, or for any other purposes. |