Alpine Immune Sciences, Inc. focuses on the discovery and development of protein-based immunotherapies for the treatment of cancer, autoimmune/inflammatory disorders, and other diseases. Its product pipeline includes ALPN-101, an inducible T cell costimulator (ICOS)/cluster of differentiation 28 (CD28) antagonist program for the. treatment of autoimmune and inflammatory diseases.
Market Cap | 828.554 Million | Shares Outstanding | 49.202 Million | Avg 30-day Volume | 588.695 Thousand |
P/E Ratio | 0.0 | Dividend Yield | 0.0 | EPS | -0.42 |
Price to Revenue | 16.9609 | Debt to Equity | 0.0 | EBITDA | -69.491 Million |
Price to Book Value | 2.9161 | Operating Margin | -224.7296 | Enterprise Value | 254.592 Million |
Current Ratio | 3.882 | EPS Growth | 0.255 | Quick Ratio | 3.821 |
1 Yr BETA | 1.4097 | 52-week High/Low | 17.25 / 5.81 | Profit Margin | -201.0748 |
Operating Cash Flow Growth | -1717.0742 | Free Cash Flow to Firm (FCFF) TTM | -71.499 Million | Free Cash Flow to Equity (FCFE) TTM | -40.532 Million |
Altman Z-Score | 2.156 |
Please sign in first
750 Thousand total shares from 2 transactions
89.5 Thousand total shares from 5 transactions
82.5 Thousand total shares from 5 transactions
Insider Name | Type | Last Reported Shares Held | Last Reported Date | Filings in past year |
---|---|---|---|---|
RICKEY JAMES PAUL SEE REMARKS |
|
0 | 2023-12-04 | 4 |
|
7,083,288 | 2023-11-09 | 2 | |
DECHENG CAPITAL GLOBAL HEALTHCARE FUND (MASTER), LP DECHENG CAPITAL GLOBAL HEALTHCARE GP, LLC |
|
1,735,544 | 2023-11-09 | 1 |
DUMMER WOLFGANG CHIEF MEDICAL OFFICER |
|
0 | 2023-10-02 | 2 |
DURAND REMY CHIEF BUSINESS OFFICER |
|
6,904 | 2023-04-21 | 1 |
SANDLER ANDREW SETH CHIEF MEDICAL OFFICER |
|
50,000 | 2023-01-05 | 1 |
GOLD MITCHELL EXECUTIVE CHAIRMAN AND CEO |
|
350,000 | 2023-01-04 | 1 |
PENG STANFORD L SEE REMARKS |
|
150,000 | 2023-01-04 | 1 |
|
10,000 | 2023-01-03 | 1 | |
|
10,000 | 2023-01-03 | 1 | |
|
10,000 | 2023-01-03 | 1 | |
|
10,000 | 2023-01-03 | 1 | |
|
10,000 | 2023-01-03 | 1 | |
|
10,000 | 2023-01-03 | 1 | |
|
6,708,288 | 2022-09-23 | 0 | |
|
2,876,372 | 2022-07-15 | 0 | |
FRAZIER LIFE SCIENCES VIII, L.P. |
|
1,484,115 | 2022-02-11 | 1 |
|
4,081,592 | 2021-09-17 | 0 | |
|
2,600,980 | 2021-09-17 | 0 | |
GOLDBERG ZELANNA CHIEF MEDICAL OFFICER |
|
0 | 2021-06-01 | 0 |
|
3,070,955 | 2020-12-28 | 0 | |
|
0 | 2020-01-02 | 0 | |
|
No longer subject to file | 2019-02-08 | 0 | |
LITTON MARK JAMES SEE REMARKS |
|
0 | 2019-02-06 | 0 |
FRAZIER LIFE SCIENCES VIII, L.P. |
|
2,716,701 | 2019-01-18 | 0 |
|
0 | 2017-07-24 | 0 | |
BIOTECHNOLOGY VALUE FUND II LP |
|
2,028,158 | 2017-06-20 | 0 |
TROHA JANICE EXEC VICE PRESIDENT / COO |
|
10,000 | 2017-05-05 | 0 |
CARRUTHERS R MICHAEL INTERIM PRESIDENT / CFO |
|
0 | 2017-01-12 | 0 |
RODMAN DAVID MALCOM EXEC VICE PRESIDENT AND CMO |
|
11,368 | 2017-01-03 | 0 |
|
0 | 2016-11-01 | 0 | |
|
0 | 2016-09-12 | 0 | |
|
0 | 2016-09-12 | 0 | |
|
0 | 2016-09-12 | 0 | |
|
0 | 2016-09-12 | 0 | |
CONGLETON JON PRESIDENT AND CEO |
|
0 | 2016-09-12 | 0 |
|
0 | 2015-09-11 | 0 | |
SHOEMAKER STEVEN VP CLINICAL R&D |
|
0 | 2015-09-11 | 0 |
GABRIEL SHERIF VICE PRESIDENT RESEARCH |
|
0 | 2015-09-11 | 0 |
DEERFIELD SPECIAL SITUATIONS FUND, L.P. DEERFIELD PRIVATE DESIGN FUND L P DEERFIELD PRIVATE DESIGN FUND II, L.P. |
|
3,732,412 | 2015-06-23 | 0 |
|
No longer subject to file | 2015-06-22 | 0 | |
|
No longer subject to file | 2015-06-22 | 0 | |
|
No longer subject to file | 2015-06-22 | 0 | |
|
1,557,228 | 2015-06-22 | 0 | |
|
No longer subject to file | 2015-06-19 | 0 | |
DEERFIELD PRIVATE DESIGN FUND L P DEERFIELD PRIVATE DESIGN INTERNATIONAL, L.P. DEERFIELD PRIVATE DESIGN FUND II, L.P. |
|
404,022 | 2015-06-16 | 0 |
|
650,915 | 2015-06-16 | 0 | |
|
501,828 | 2011-03-14 | 0 |
Reporting Owners | Filing Date | Trans Date | Trans Code | Shares | Share Price | Acquired Disposed |
Shares Owned after | D/I | 10b5 | Perf 1d* | Perf 5d* | Perf 1m* | Max Gain | Max Gain Days | Max Loss | Max Loss Days |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2023-12-06 19:31:13 -0500 | 2023-12-06 | M | 6,446 | d | 19,500 | direct | yes | |||||||||
2023-12-06 19:31:13 -0500 | 2023-12-06 | S | 6,446 | $16.08 | d | 0 | direct | yes | 1.937 | 1.937 | 2 | 0.0 | 1 | |||
2023-12-06 19:31:13 -0500 | 2023-12-06 | M | 6,446 | $3.23 | a | 6,446 | direct | yes | 1.937 | 1.937 | 2 | 0.0 | 1 | |||
2023-12-06 19:31:13 -0500 | 2023-12-05 | M | 418 | d | 25,946 | direct | yes | |||||||||
2023-12-06 19:31:13 -0500 | 2023-12-05 | S | 418 | $16.01 | d | 0 | direct | yes | 1.937 | 1.937 | 2 | 0.0 | 1 | |||
2023-12-06 19:31:13 -0500 | 2023-12-05 | M | 418 | $3.23 | a | 418 | direct | yes | 1.937 | 1.937 | 2 | 0.0 | 1 | |||
2023-12-06 19:31:13 -0500 | 2023-12-04 | M | 63,947 | d | 26,364 | direct | yes | |||||||||
2023-12-06 19:31:13 -0500 | 2023-12-04 | S | 63,947 | $16.06 | d | 0 | direct | yes | 1.937 | 1.937 | 2 | 0.0 | 1 | |||
2023-12-06 19:31:13 -0500 | 2023-12-04 | M | 63,947 | $3.23 | a | 63,947 | direct | yes | 1.937 | 1.937 | 2 | 0.0 | 1 | |||
2023-12-01 17:00:44 -0500 | 2023-11-30 | M | 700 | d | 90,311 | direct | yes | |||||||||
2023-12-01 17:00:44 -0500 | 2023-11-30 | S | 700 | $16.00 | d | 0 | direct | yes | -4.1199 | 0.0 | 1 | -4.1199 | 2 | |||
2023-12-01 17:00:44 -0500 | 2023-11-30 | M | 700 | $3.23 | a | 700 | direct | yes | -4.1199 | 0.0 | 1 | -4.1199 | 2 | |||
CUI XIANGMIN - Director - > 10% Owner see footnote |
2023-11-14 17:33:22 -0500 | 2023-11-09 | P | 375,000 | $12.50 | a | 1,735,544 | indirect | 0.2375 | 9.0261 | 11.0847 | 4 | 0.0 | 1 | ||
DECHENG CAPITAL GLOBAL HEALTHCARE FUND (MASTER), LP - > 10% Owner |
2023-11-14 17:36:42 -0500 | 2023-11-09 | P | 375,000 | $12.50 | a | 1,735,544 | direct | 0.2375 | 9.0261 | 11.0847 | 4 | 0.0 | 1 | ||
2023-11-08 17:20:54 -0500 | 2023-11-06 | S | 18,003 | $16.03 | d | 0 | direct | yes | 1.3267 | 4.9751 | 4.9751 | 6 | -4.1459 | 3 | ||
2023-11-08 17:20:54 -0500 | 2023-11-06 | M | 10,989 | d | 91,011 | direct | yes | |||||||||
2023-11-08 17:20:54 -0500 | 2023-11-06 | M | 10,989 | $3.23 | a | 18,003 | direct | yes | 1.3267 | 4.9751 | 4.9751 | 6 | -4.1459 | 3 |
* -
Code | Definition |
---|---|
A | Grant, award or other acquisition pursuant to Rule 16b-3(d) |
C | Conversion of derivative security |
D | Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e) |
E | Expiration of short derivative position |
F | Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3 |
G | Bona fide gift |
H | Expiration (or cancellation) of long derivative position with value received |
I | Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities |
J | Other acquisition or disposition |
L | Small acquisition under Rule 16a-6 |
M | Exercise or conversion of derivative security exempted pursuant to Rule 16b-3 |
O | Exercise of out-of-the-money derivative security |
P | Open market or private purchase of non-derivative or derivative security |
S | Open market or private sale of non-derivative or derivative security |
U | Disposition pursuant to a tender of shares in a change of control transaction |
W | Acquisition or disposition by will or the laws of descent and distribution |
X | Exercise of in-the-money or at-the-money derivative security |
Z | Deposit into or withdrawal from voting trust |
Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers
Security | Date/Time | Rebate Rate | Fee Rate | Shares Available |
---|---|---|---|---|
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 22:15:04 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 21:45:04 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 21:15:04 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 20:45:04 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 20:15:07 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 19:45:04 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 19:15:03 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 18:45:03 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 18:15:04 UTC | 4.4973 | 0.8227 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 17:45:03 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 17:15:03 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 16:45:05 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 16:15:04 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 15:45:04 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 15:15:04 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 14:45:04 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 14:15:03 UTC | 4.4451 | 0.8749 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 13:45:03 UTC | 4.558 | 0.762 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 13:15:04 UTC | 4.558 | 0.762 | 650000 |
ALPINE IMMUNE SCIENCES INC ALPN | 2023-12-08 12:45:05 UTC | 4.558 | 0.762 | 650000 |
Holder | Issuer | Net Short Position | Position Date | Origin |
---|