Applied Therapeutics Inc (APLT)

Sector:
HEALTH CARE
Industry:
BIOTECHNOLOGY & LIFE SCIENCES
SIC:
PHARMACEUTICAL PREPARATIONS
CEO:
Shoshana Shendelman
Employees:
30
340 MADISON AVENUE, 19TH FLOOR, NEW YORK, NY 10173
212-220-9319

Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel products to target cardiovascular disease, galactosemia, and diabetic complications. Its lead product candidate is AT-007 that has completed phase 1/2 for the treatment of galactosmia in healthy volunteers and adults. The company also develops AT-001 that is in phase III clinical trials for treating diabetic cardiomyopathy, as well as for treatment of diabetic peripheral neuropathy.

Data derived from most recent annual or quarterly report
Market Cap 29.91 Million Shares Outstanding26.237 Million Avg 30-day Volume 200.88 Thousand
P/E Ratio0.0 Dividend Yield0.0 EPS-1.09
Price to Revenue0.0 Debt to Equity0.0 EBITDA-100.273 Million
Price to Book Value1.3182 Operating Margin0.0 Enterprise Value-336.266 Thousand
Current Ratio2.861 EPS Growth0.147 Quick Ratio2.505
1 Yr BETA 1.2165 52-week High/Low 19.14 / 0.73 Profit Margin0.0
Operating Cash Flow Growth-13.9247 Altman Z-Score-9.3698 Free Cash Flow to Firm -72.314 Million
Earnings Report2022-08-11
View SEC Filings from APLT instead.

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Funds Holding APLT (via 13F filings)

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Recent Filings

Events (8k)

  • 8-K: filed on 2022-08-04:
    Item 8.01: Other Events
  • 8-K: filed on 2022-06-27:
    Item 1.01: Entry into a Material Definitive Agreement
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2022-06-03:
    Item 5.07: Submission of Matters to a Vote of Security Holders
  • 8-K: filed on 2022-05-12:
    Item 2.02: Results of Operations and Financial Condition
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2022-03-10:
    Item 2.02: Results of Operations and Financial Condition
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2022-02-15:
    Item 7.01: Regulation FD Disclosure
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2022-01-26:
    Item 2.02: Results of Operations and Financial Condition
    Item 8.01: Other Events
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2021-11-12:
    Item 2.02: Results of Operations and Financial Condition
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2021-08-12:
    Item 2.02: Results of Operations and Financial Condition
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2021-06-04:
    Item 5.07: Submission of Matters to a Vote of Security Holders
  • Open Market Buys/Sells Last 60 Days

    Open Market Buys (P)

    10 Million total shares from 6 transactions

    Open Market Sells (S)

    none

    Exercise Derivative Conversion (M)

    none

    Current/Former Insiders

    Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

    MARCUS JOEL S

    • Director
    34,119 2022-08-02 2

    SKYLER JAY S

    • Director
    47,190 2022-08-02 2

    FUNTLEYDER LESLIE D.

    • Director
    47,190 2022-08-02 2

    LERNER TEENA

    • Director
    47,190 2022-08-02 2

    KANTER STACY J.

    • Director
    47,190 2022-08-02 2

    PERFETTI RICCARDO CHIEF MEDICAL OFFICER

    • Officer
    305,258 2022-08-02 6

    SHENDELMAN SHOSHANA PRESIDENT AND CEO

    • Officer
    • Director
    • 10% Owner
    1,102,066 2022-08-02 6

    HANSARD ADAM CHIEF COMMERCIAL OFFICER

    • Officer
    208,104 2022-08-02 5

    MAHADEVAN CHIDS SEE REMARKS

    • Officer
    35,146 2022-08-02 3

    ALEXANDRIA REAL ESTATE EQUITIES, INC.

    ALEXANDRIA VENTURE INVESTMENTS, LLC

    ALEXANDRIA EQUITIES NO. 7, LLC

    • 10% Owner
    12,819,054 2022-06-27 2

    ORTEGA STEVEN A. PRINCIPAL ACCOUNTING OFFICER

    • Officer
    26,079 2022-04-13 2

    SILBERSTEIN CHARLES CHIEF FINANCIAL OFFICER

    • Officer
    215,603 2022-01-07 3

    ALEXANDRIA REAL ESTATE EQUITIES INC

    ALEXANDRIA VENTURE INVESTMENTS, LLC

    • 10% Owner
    0 2019-05-13 2

    VIGNOLA MARK J. CHIEF FINANCIAL OFFICER

    • Officer
    0 2019-05-13 0

    Insider Transactions Last 60 Days

    Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
    Disposed
    Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

    MAHADEVAN CHIDS - Officer SEE REMARKS

    2022-08-04 20:38:14 -0400 2022-08-02 D 8,824 d 0 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 51,666 d 0 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 36,495 a 36,495 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 36,495 d 0 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 32,100 a 32,100 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 32,100 d 0 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 32,100 a 32,100 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 32,100 d 0 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 50,000 a 50,000 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 50,000 d 0 direct

    MAHADEVAN CHIDS - Officer SEE REMARKS

    2022-08-04 20:38:14 -0400 2022-08-02 D 8,824 a 8,824 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 51,666 a 51,666 direct

    MAHADEVAN CHIDS - Officer SEE REMARKS

    2022-08-04 20:38:14 -0400 2022-08-02 D 7,264 a 7,264 direct

    MAHADEVAN CHIDS - Officer SEE REMARKS

    2022-08-04 20:38:14 -0400 2022-08-02 D 7,264 d 0 direct

    MAHADEVAN CHIDS - Officer SEE REMARKS

    2022-08-04 20:38:14 -0400 2022-08-02 D 19,058 a 19,058 direct

    MAHADEVAN CHIDS - Officer SEE REMARKS

    2022-08-04 20:38:14 -0400 2022-08-02 D 19,058 d 0 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 7,389 a 7,389 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 7,389 d 0 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 10,230 a 10,230 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 10,230 d 0 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 16,500 a 16,500 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 20,460 a 20,460 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 607,484 a 607,484 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 607,484 d 0 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 23,317 a 23,317 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 23,317 d 0 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 134,979 a 134,979 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 134,979 d 0 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 101,670 a 101,670 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 101,670 d 0 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 234,616 a 234,616 direct

    SHENDELMAN SHOSHANA - Director - Officer - > 10% Owner PRESIDENT AND CEO

    2022-08-04 20:40:54 -0400 2022-08-02 D 234,616 d 0 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 16,500 d 0 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 20,460 d 0 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 10,230 a 10,230 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 10,230 d 0 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 16,500 a 16,500 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 16,500 d 0 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 16,500 a 16,500 direct

    SKYLER JAY S - Director

    2022-08-04 20:41:30 -0400 2022-08-02 D 16,500 d 0 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 134,997 a 134,997 direct

    PERFETTI RICCARDO - Officer CHIEF MEDICAL OFFICER

    2022-08-04 20:39:55 -0400 2022-08-02 D 134,997 d 0 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 16,500 d 0 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 50,000 a 50,000 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 50,000 d 0 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 20,460 a 20,460 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 20,460 d 0 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 10,230 a 10,230 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 10,230 d 0 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 16,500 a 16,500 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 16,500 d 0 direct

    KANTER STACY J. - Director

    2022-08-04 20:36:38 -0400 2022-08-02 D 16,500 a 16,500 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 16,500 a 16,500 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 20,460 a 20,460 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 20,460 d 0 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 10,230 a 10,230 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 10,230 d 0 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 16,500 a 16,500 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 16,500 d 0 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 16,500 a 16,500 direct

    FUNTLEYDER LESLIE D. - Director

    2022-08-04 20:35:05 -0400 2022-08-02 D 16,500 d 0 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 21,100 a 21,100 direct

    MARCUS JOEL S - Director

    2022-08-04 20:39:02 -0400 2022-08-02 D 16,500 d 0 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 20,460 a 20,460 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 20,460 d 0 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 10,230 a 10,230 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 10,230 d 0 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 16,500 a 16,500 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 16,500 d 0 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 16,500 a 16,500 direct

    LERNER TEENA - Director

    2022-08-04 20:37:13 -0400 2022-08-02 D 16,500 d 0 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 104,665 a 104,665 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 104,665 d 0 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 32,339 a 32,339 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 32,339 d 0 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 21,100 a 21,100 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 21,100 d 0 direct

    HANSARD ADAM - Officer CHIEF COMMERCIAL OFFICER

    2022-08-04 20:35:49 -0400 2022-08-02 D 21,100 d 0 direct

    ALEXANDRIA REAL ESTATE EQUITIES, INC. - > 10% Owner by subsidiary

    ALEXANDRIA VENTURE INVESTMENTS, LLC - > 10% Owner by subsidiary

    ALEXANDRIA EQUITIES NO. 7, LLC - > 10% Owner by subsidiary

    2022-06-29 16:37:37 -0400 2022-06-27 P 1,435,000 $1.00 a 2,378,977 indirect -8.7553 -0.5274 0.0 1 -8.7553 2

    ALEXANDRIA REAL ESTATE EQUITIES, INC. - > 10% Owner by subsidiary

    ALEXANDRIA VENTURE INVESTMENTS, LLC - > 10% Owner by subsidiary

    ALEXANDRIA EQUITIES NO. 7, LLC - > 10% Owner by subsidiary

    2022-06-29 16:37:37 -0400 2022-06-27 P 2,950,000 a 2,950,000 indirect

    ALEXANDRIA REAL ESTATE EQUITIES, INC. - > 10% Owner by subsidiary

    ALEXANDRIA VENTURE INVESTMENTS, LLC - > 10% Owner by subsidiary

    ALEXANDRIA EQUITIES NO. 7, LLC - > 10% Owner by subsidiary

    2022-06-29 16:37:37 -0400 2022-06-27 P 2,050,000 a 2,050,000 indirect

    ALEXANDRIA REAL ESTATE EQUITIES, INC. - > 10% Owner by subidiary

    ALEXANDRIA VENTURE INVESTMENTS, LLC - > 10% Owner by subidiary

    ALEXANDRIA EQUITIES NO. 7, LLC - > 10% Owner by subidiary

    2022-06-29 16:37:37 -0400 2022-06-27 P 885,000 $1.00 a 885,000 indirect

    ALEXANDRIA REAL ESTATE EQUITIES, INC. - > 10% Owner by subsidiary

    ALEXANDRIA VENTURE INVESTMENTS, LLC - > 10% Owner by subsidiary

    ALEXANDRIA EQUITIES NO. 7, LLC - > 10% Owner by subsidiary

    2022-06-29 16:37:37 -0400 2022-06-27 P 615,000 $1.00 a 615,000 indirect

    ALEXANDRIA REAL ESTATE EQUITIES, INC. - > 10% Owner by subsidiary

    ALEXANDRIA VENTURE INVESTMENTS, LLC - > 10% Owner by subsidiary

    ALEXANDRIA EQUITIES NO. 7, LLC - > 10% Owner by subsidiary

    2022-06-29 16:37:37 -0400 2022-06-27 P 2,065,000 $1.00 a 4,555,077 indirect -8.7553 -0.5274 0.0 1 -8.7553 2

    * -

    Transaction Code Definitions
    Code Definition
    A Grant, award or other acquisition pursuant to Rule 16b-3(d)
    C Conversion of derivative security
    D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
    E Expiration of short derivative position
    F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
    G Bona fide gift
    H Expiration (or cancellation) of long derivative position with value received
    I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
    J Other acquisition or disposition
    L Small acquisition under Rule 16a-6
    M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
    O Exercise of out-of-the-money derivative security
    P Open market or private purchase of non-derivative or derivative security
    S Open market or private sale of non-derivative or derivative security
    U Disposition pursuant to a tender of shares in a change of control transaction
    W Acquisition or disposition by will or the laws of descent and distribution
    X Exercise of in-the-money or at-the-money derivative security
    Z Deposit into or withdrawal from voting trust

    IBR Securities Loan Availability

    Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

    Security Date/Time Rebate Rate Fee Rate Shares Available
    APPLIED THERAPEUTICS INC APLT 2022-08-10 20:15:06 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 19:45:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 19:15:05 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 18:45:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 18:15:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 17:45:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 17:15:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 16:45:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 16:15:03 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 15:45:05 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 15:15:05 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 14:45:04 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 14:15:03 UTC 0.6372 1.6828 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 13:45:03 UTC 1.0166 1.3034 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 13:15:04 UTC 1.0166 1.3034 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-10 12:45:05 UTC 1.0166 1.3034 200000
    APPLIED THERAPEUTICS INC APLT 2022-08-09 22:15:07 UTC 1.0166 1.3034 150000
    APPLIED THERAPEUTICS INC APLT 2022-08-09 21:45:04 UTC 1.0166 1.3034 150000
    APPLIED THERAPEUTICS INC APLT 2022-08-09 21:15:04 UTC 1.0166 1.3034 150000
    APPLIED THERAPEUTICS INC APLT 2022-08-09 20:45:03 UTC 1.0166 1.3034 150000

    Current Active Short Positions

    Holder Issuer Net Short Position Position Date Origin
    FundVantage Trust- Gotham Enhanced Index Plus Fund APLT -7.0 shares, $-228.83 2020-03-31 N-PORT
    FundVantage Trust- Gotham Index Plus All-Cap Fund APLT -7.0 shares, $-228.83 2020-03-31 N-PORT

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