Ayala Pharmaceuticals, Inc. (AYLA)

HEALTH CARE: BIOTECHNOLOGY & LIFE SCIENCES
SIC: BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES)

1313 N. MARKET STREET WILMINGTON, DE 19801

Ayala Pharmaceuticals, Inc. is a clinical-stage oncology company focused on developing and commercializing small molecule therapeutics for patients suffering from rare and aggressive cancers. Ayala's approach is focused on predicating, identifying and addressing tumorigenic drivers of cancer through a combination of its bioinformatics platform and next-generation sequencing to deliver targeted therapies to underserved patient populations. The company has two product candidates under development, AL101 and AL102, targeting the aberrant activation of the Notch pathway with gamma secretase inhibitors to treat a variety of tumors including Adenoid Cystic Carcinoma, Triple Negative Breast Cancer (TNBC), T-cell Acute Lymphoblastic Leukemia (T-ALL), Desmoid Tumors and Multiple Myeloma (MM) (in collaboration with Novartis). AL101 has received Fast Track Designation and Orphan Drug Designation from the U.S. FDA and is currently in a Phase 2 clinical trial for patients with ACC (ACCURACY) bearing Notch activating mutations and in a Phase 2 clinical trial for patients with TNBC (TENACITY) bearing Notch activating mutations and other gene rearrangements. AL102 is currently being advanced to a Phase 2/3 clinical trials for patients with desmoid tumors (RINGSIDE).

Data as of 2021-10-09 10:47:39 -0400
Market Cap132.561 Million Shares Outstanding13.243 Million Avg 30-day Volume50.115 Thousand
P/E Ratio0.0 Dividend Yield0.0 EPS0
Price/Sales Debt to Equity EBITDA
Price to Book Value0.0 Forward PE-4.37 Enterprise Value
Total Cash Current Debt Gross Profit
BETA0.70803 52-week High/Low28.68 / 7.74 Next Earnings Date2021-11-15 Price to Cash FLow (P/CF) -9999999.0
Data provided by IEX Cloud
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Funds Holding AYLA (via 13F filings)

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Mutual Funds Holding AYLA BETA

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Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

none

Open Market Sells (S)

none

Exercise Derivative Conversion (M)

none

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

GOLDBERG MURRAY A

  • Director
6,250 2021-06-10 1

SIDRANSKY DAVID

  • Director
12,500 2021-06-10 1

SPIEGEL ROBERT J.

  • Director
6,250 2021-06-10 1

SONE TODD

  • Director
6,250 2021-06-10 1

BISKER-LEIB VERED

  • Director
6,250 2021-06-10 1

GORDON GARY B. CHIEF MEDICAL OFFICER

  • Officer
97,520 2021-02-24 3

MAMLUK RONI PRESIDENT & CEO

  • Officer
  • Director
145,345 2021-02-22 3

MAIMON YOSSI CFO, SECRETARY & TREASURER

  • Officer
19,872 2021-01-04 1

HAREL INSURANCE CO LTD

HAREL INSURANCE INVESTMENTS & FINANCIAL SERVICES LTD.

  • 10% Owner
2,163,834 2020-05-12 0

ISRAEL BIOTECH FUND I, L.P.

  • 10% Owner
3,315,119 2020-05-12 0

AMOON 2 FUND LIMITED PARTNERSHIP

  • 10% Owner
2,991,473 2020-05-12 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed
Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days
No current insider transactions

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

IBR Securities Loan Availability

Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

Security Date/Time Rebate Rate Fee Rate Shares Available
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 22:15:04 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 21:45:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 21:15:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 20:45:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 20:15:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 19:45:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 19:15:04 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 18:45:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 18:15:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 17:45:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 17:15:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 16:45:03 UTC -4.7352 4.8052 80000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 16:15:03 UTC -4.7352 4.8052 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 15:45:03 UTC -4.7352 4.8052 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 15:15:03 UTC -4.7352 4.8052 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 14:45:02 UTC -4.4654 4.5354 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 14:15:03 UTC -4.4654 4.5354 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 13:45:03 UTC -4.4654 4.5354 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 13:15:03 UTC -4.4654 4.5354 4000
AYALA PHARMACEUTICALS INC AYLA 2021-10-15 12:45:03 UTC -4.4654 4.5354 4000

Current Active Short Positions

Holder Issuer Net Short Position Position Date Origin

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