Constellation Pharmaceuticals Inc (CNST)

HEALTH CARE: PHARMACEUTICALS
SIC: PHARMACEUTICAL PREPARATIONS

215 FIRST STREET CAMBRIDGE, MA 02142

Constellation Pharmaceuticals is a clinical-stage biopharmaceutical company developing novel therapeutics that selectively modulate gene expression to address serious unmet medical needs in patients with cancer. The Company has a deep understanding of how epigenetic and chromatin modifications in cancer cells and in the tumor and immune microenvironment play a fundamental role in driving disease progression and drug resistance. Constellation is driving development of the BET inhibitor CPI-0610 for the treatment of myelofibrosis as well as the EZH2 inhibitor CPI-0209 for the treatment of solid tumors. The Company is also applying its broad research and development capabilities to explore other novel targets that directly and indirectly impact gene expression to fuel a sustainable pipeline of innovative small-molecule product candidates.

Data as of 2021-07-25 17:36:37 -0400
Market Cap0 Shares Outstanding47.915 Million Avg 30-day Volume0
P/E Ratio0.0 Dividend Yield0.0 EPS0
Price/Sales Debt to Equity EBITDA
Price to Book Value0.0 Forward PE Enterprise Value
Total Cash Current Debt Gross Profit
BETA0.0 52-week High/Low0.0 / 0.0 Next Earnings Date Price to Cash FLow (P/CF) -40.3711
Data provided by IEX Cloud
View SEC Filings from CNST instead.
Q1 2021 All 13F Filers Prior Change Hedge Funds 1 Prior Change
In top 10: 7 10 -30.0% 1 (0.06%) 4 (0.23%) -75.0%
Funds Holding: 130 134 -2.99% 46 (2.7%) 49 (2.84%) -6.12%
13F shares: 51.818 Million 50.7 Million 2.21% 26.95 Million 26.722 Million 0.85%
% Ownership 56.6461 56.1678 0.85%
New Positions: 13 35 -62.86% 7 14 -50.0%
Increased Positions 49 36 36.11% 16 11 45.45%
Closed Positions 17 21 -19.05% 10 12 -16.67%
Reduced Positions 43 42 2.38% 18 20 -10.0%
Total Calls 248.101 Thousand 45.582 Thousand 444.3% 52.8 Thousand 18.6 Thousand 183.87%
Total Puts 352.749 Thousand 72.186 Thousand 388.67% 84 Thousand 17.2 Thousand 388.37%
PUT/CALL Ratio 1.42 1.58 -10.13% 1.59 0.92 72.83%
1 hedge funds and active managers as identified by whalewisdom.com through public filings.

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Funds Holding CNST (via 13F filings)

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*Please note that if a filer hasn't submitted a 13F filing for a quarter then the filer's shares will be listed as "Sold All"

Mutual Funds Holding CNST BETA

Active Schedule 13D and 13G filings

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Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

none

Open Market Sells (S)

none

Exercise Derivative Conversion (M)

none

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

GOLDSMITH MARK A

0 2021-07-15 6

HOERTER STEVEN L.

0 2021-07-15 3

AUDIA JAMES E

0 2021-07-15 2

TREHU ELIZABETH

0 2021-07-15 2

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

0 2021-07-15 2

REEVE EMMA CHIEF FINANCIAL OFFICER

0 2021-07-15 5

RAYTHATHA JIGAR SEE REMARKS

0 2021-07-15 2

VALENTINE KAREN SEE REMARKS

0 2021-07-15 3

LEVY RICHARD S

0 2021-07-15 2

BRAUNSTEIN SCOTT

0 2021-07-15 2

HUMPHREY JEFFREY CHIEF MEDICAL OFFICER

0 2021-07-15 2

COLUMN GROUP L P

COLUMN GROUP III, LP

COLUMN GROUP III-A, LP

COLUMN GROUP III GP, LP

COLUMN GROUP GP, LP

PONOI CAPITAL, LP

PONOI MANAGEMENT, LLC

PONOI CAPITAL II, LP

PONOI II MANAGEMENT, LLC

KUTZKEY TIM

  • 10% Owner
6,230,638 2021-02-17 1

COLUMN GROUP L P

GOEDDEL DAVID V

SVENNILSON PETER

  • 10% Owner
6,230,638 2021-02-17 1

SENDEROWICZ ADRIAN CHIEF MEDICAL OFFICER

15,884 2020-05-12 0

COLUMN GROUP L P

COLUMN GROUP GP, LP

PONOI CAPITAL, LP

PONOI MANAGEMENT, LLC

PONOI CAPITAL II, LP

PONOI II MANAGEMENT, LLC

KUTZKEY TIM

GOEDDEL DAVID V

SVENNILSON PETER

  • 10% Owner
  • GENERAL PARTNER GENERAL PARTNERMANAGING PARTNERMANAGING PARTNERMANAGING PARTNER
6,210,531 2020-03-19 0

COLUMN GROUP III, LP

COLUMN GROUP III-A, LP

COLUMN GROUP III GP, LP

  • 10% Owner
  • GENERAL PARTNER
36,135 2020-03-19 0

COLUMN GROUP L P

COLUMN GROUP III, LP

COLUMN GROUP III-A, LP

COLUMN GROUP III GP, LP

  • 10% Owner
  • GENERAL PARTNER
6,210,531 2020-03-19 2

EVNIN ANTHONY B

  • Director
5,742,765 2019-12-13 0

VENROCK HEALTHCARE CAPITAL PARTNERS III, L.P.

VHCP CO-INVESTMENT HOLDINGS III, LLC

VHCP MANAGEMENT III, LLC

VENROCK HEALTHCARE CAPITAL PARTNERS II, L.P.

VHCP CO-INVESTMENT HOLDINGS II, LLC

VHCP MANAGEMENT II, LLC

KOH BONG Y

SHAH NIMISH P

  • 10% Owner
4,016,873 2019-12-13 0

REGENTS OF THE UNIVERSITY OF CALIFORNIA

2,110,290 2019-11-08 0

TEPPER ROBERT I

  • Director
  • 10% Owner
0 2019-06-06 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed
Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 141,929 d 0 direct

LEVY RICHARD S

2021-07-19 17:27:39 -0400 2021-07-15 D 13,171 d 0 direct

HUMPHREY JEFFREY CHIEF MEDICAL OFFICER

2021-07-19 18:45:00 -0400 2021-07-15 D 35,055 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 306,938 d 0 direct

HOERTER STEVEN L.

2021-07-19 17:35:12 -0400 2021-07-15 D 13,171 d 0 direct

VALENTINE KAREN SEE REMARKS

2021-07-19 17:41:23 -0400 2021-07-15 D 22,425 d 0 direct

HOERTER STEVEN L.

2021-07-19 17:35:12 -0400 2021-07-15 D 13,171 d 0 direct

TREHU ELIZABETH

2021-07-19 17:40:22 -0400 2021-07-15 D 13,171 d 0 direct

TREHU ELIZABETH

2021-07-19 17:40:22 -0400 2021-07-15 D 13,171 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 12,446 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 17,312 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 13,171 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 850 d 0 direct

BRAUNSTEIN SCOTT

2021-07-19 17:33:23 -0400 2021-07-15 D 26,342 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 22,708 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 11,626 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 80,971 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 24,604 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 73,428 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 13,171 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 204,500 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 25,434 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 141,929 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 200,000 d 0 direct

HUMPHREY JEFFREY CHIEF MEDICAL OFFICER

2021-07-19 18:45:00 -0400 2021-07-15 D 133,000 d 0 direct

HOERTER STEVEN L.

2021-07-19 17:35:12 -0400 2021-07-15 D 26,342 d 0 direct

VALENTINE KAREN SEE REMARKS

2021-07-19 17:41:23 -0400 2021-07-15 D 81,939 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 13,171 d 0 direct

TREHU ELIZABETH

2021-07-19 17:40:22 -0400 2021-07-15 D 26,342 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 55,000 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 13,171 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 40,000 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 89,857 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 43,387 d 0 direct

BRAUNSTEIN SCOTT

2021-07-19 17:33:23 -0400 2021-07-15 D 13,171 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 72,050 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 9,083 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 17,666 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 9,083 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 37,527 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 8,175 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 423,940 d 0 direct

LEVY RICHARD S

2021-07-19 17:27:39 -0400 2021-07-15 D 26,342 d 0 direct

HOERTER STEVEN L.

2021-07-23 16:27:58 -0400 2021-07-15 D 26,342 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 245,000 d 0 direct

RAYTHATHA JIGAR SEE REMARKS

2021-07-19 17:37:06 -0400 2021-07-15 D 14,961 d 0 direct

VALENTINE KAREN SEE REMARKS

2021-07-19 17:41:23 -0400 2021-07-15 D 41,800 d 0 direct

HOERTER STEVEN L.

2021-07-19 17:35:12 -0400 2021-07-15 D 13,171 d 0 direct

VALENTINE KAREN SEE REMARKS

2021-07-19 17:41:23 -0400 2021-07-15 D 58,600 d 0 direct

TREHU ELIZABETH

2021-07-19 17:40:22 -0400 2021-07-15 D 13,171 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 9,083 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 3,121 d 0 direct

GOLDSMITH MARK A

2021-07-19 17:34:01 -0400 2021-07-15 D 6,825 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 33,330 d 0 direct

BRAUNSTEIN SCOTT

2021-07-19 17:33:23 -0400 2021-07-15 D 13,171 d 0 direct

TROJER PATRICK CHIEF SCIENTIFIC OFFICER

2021-07-19 17:40:13 -0400 2021-07-15 D 78,000 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 13,171 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 66,950 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 2,384 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 11,777 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 1,277 d 0 direct

REEVE EMMA CHIEF FINANCIAL OFFICER

2021-07-19 17:38:22 -0400 2021-07-15 D 60,000 d 0 direct

AUDIA JAMES E

2021-07-19 17:29:02 -0400 2021-07-15 D 13,171 d 0 direct

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

IBR Securities Loan Availability

Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

Security Date/Time Rebate Rate Fee Rate Shares Available
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 22:15:03 UTC -1.3235 1.4035 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 21:45:02 UTC -1.3235 1.4035 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 21:15:03 UTC -1.3235 1.4035 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 20:45:03 UTC -1.3235 1.4035 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 20:15:03 UTC -1.3235 1.4035 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 19:45:03 UTC -1.0698 1.1498 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 19:15:03 UTC -1.0698 1.1498 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 18:45:03 UTC -1.0972 1.1772 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 18:15:03 UTC -1.0972 1.1772 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 17:45:03 UTC -1.0972 1.1772 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 17:15:03 UTC -1.0972 1.1772 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 16:45:03 UTC -1.0813 1.1613 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 16:15:02 UTC -1.0813 1.1613 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 15:45:03 UTC -1.309 1.389 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 15:15:03 UTC -1.309 1.389 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 14:45:03 UTC -0.332 0.412 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 14:15:04 UTC -0.332 0.412 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 13:45:02 UTC -0.332 0.412 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 13:15:03 UTC -0.332 0.412 400000
CONSTELLATION PHARMACEUTICAL CNST 2021-07-15 12:45:03 UTC -0.332 0.412 400000

Current Active Short Positions

Holder Issuer Net Short Position Position Date Origin

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