Denali Therapeutics Inc (DNLI)

HEALTH CARE: BIOTECHNOLOGY & LIFE SCIENCES
SIC: BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES)

161 OYSTER POINT BLVD. SOUTH SAN FRANCISCO, CA 94080

Denali Therapeutics is a biopharmaceutical company developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for neurodegenerative diseases. Denali pursues new treatments by rigorously assessing genetically validated targets, engineering delivery across the BBB and guiding development through biomarkers that demonstrate target and pathway engagement. Denali is based in South San Francisco.

Data as of 2021-07-19 09:44:11 -0400
Market Cap7.811 Billion Shares Outstanding121.192 Million Avg 30-day Volume764.37 Thousand
P/E Ratio135.00014 Dividend Yield EPS0.493
Price/Sales22.97 Debt to Equity1.4 EBITDA59.995 Million
Price to Book Value7.07 Forward PE-0.07 Enterprise Value6.398 Billion
Total Cash1.413 Billion Current Debt54.61 Million Gross Profit339.978 Million
BETA1.22047 52-week High/Low93.94 / 22.36 Next Earnings Date2021-08-06 Price to Cash FLow (P/CF) -135.4893
Data provided by IEX Cloud
View SEC Filings from DNLI instead.
Q1 2021 All 13F Filers Prior Change Hedge Funds 1 Prior Change
In top 10: 5 5 0.0% 1 (0.06%) 3 (0.17%) -66.67%
Funds Holding: 213 203 4.93% 73 (4.28%) 60 (3.48%) 21.67%
13F shares: 79.848 Million 88.61 Million -9.89% 20.773 Million 27.59 Million -24.71%
% Ownership 65.9985 73.8916 -10.68% 17.17 23.0073 -25.37%
New Positions: 41 60 -31.67% 22 19 15.79%
Increased Positions 78 62 25.81% 30 11 172.73%
Closed Positions 27 24 12.5% 6 14 -57.14%
Reduced Positions 67 65 3.08% 16 24 -33.33%
Total Calls 249.244 Thousand 354.62 Thousand -29.72% 187.9 Thousand 121.2 Thousand 55.03%
Total Puts 74.61 Thousand 68.802 Thousand 8.44% 19.3 Thousand 51.8 Thousand -62.74%
PUT/CALL Ratio 0.3 0.19 57.89% 0.1 0.43 -76.74%
1 hedge funds and active managers as identified by whalewisdom.com through public filings.

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Funds Holding DNLI (via 13F filings)

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Mutual Funds Holding DNLI BETA

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Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

none

Open Market Sells (S)

156 Thousand total shares from 20 transactions

Exercise Derivative Conversion (M)

113.9 Thousand total shares from 9 transactions

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

SATO VICKI L

  • Director
132,831 2021-07-21 7

SCHUTH ALEXANDER O. COO AND SECRETARY

  • Officer
583,036 2021-07-06 12

WATTS RYAN J. PRESIDENT AND CEO

  • Officer
  • Director
2,349,100 2021-07-01 10

TESSIER-LAVIGNE MARC

  • Director
2,552,232 2021-06-07 6

COLE DOUGLAS G.

  • Director
11,549 2021-06-02 2

FLATLEY JAY T

  • Director
336,549 2021-06-02 2

NELSEN ROBERT

  • Director
9,687,403 2021-06-02 2

SCHENKEIN DAVID P

  • Director
69,013 2021-06-02 6

KLEIN PETER S

  • Director
11,549 2021-06-02 2

COOK JENNIFER E.

  • Director
11,549 2021-06-02 2

HO CAROLE CHIEF MEDICAL OFFICER

  • Officer
269,701 2021-03-29 9

KROGNES STEVE E. CFO AND TREASURER

  • Officer
947,587 2021-03-15 8

BRATTON DOUGLAS K

AKDL, L.P.

CRESTLINE SI (GP), L.P.

CRESTLINE INVESTORS, INC.

CRESTLINE MANAGEMENT, LP

  • 10% Owner
No longer subject to file 2021-02-12 3

THORNBERRY NANCY

  • Director
0 2021-01-08 2

BRATTON DOUGLAS K

NEURO LINE PARTNERS LP

BRATTON CAPITAL MANAGEMENT, L.P.

BRATTON CAPITAL INC.

  • 10% Owner
12,201,634 2020-12-21 1

BIOGEN INC.

BIOGEN MA INC.

  • 10% Owner
13,310,243 2020-09-22 1

ARCH VENTURE FUND VIII, L.P.

ARCH VENTURE PARTNERS VIII, L.P.

ARCH VENTURE PARTNERS VIII, LLC

BYBEE CLINTON

CRANDELL KEITH

  • 10% Owner
10,668,749 2019-08-08 0

SCHUTH ALEXANDER O. COO AND SECRETARY

SCHUTH ALEXANDER O. COO AND SECRETARY

  • Officer
686,565 2019-03-11 12

FMR LLC

  • SEE REMARK 1
No longer subject to file 2018-04-09 0

FIL LTD

  • SEE REMARK 1
No longer subject to file 2017-12-12 0

BRATTON DOUGLAS K

AKDL, L.P.

NEURO LINE PARTNERS LP

CRESTLINE SI (GP), L.P.

CRESTLINE INVESTORS, INC.

BRATTON CAPITAL MANAGEMENT, L.P.

BRATTON CAPITAL INC.

CRESTLINE MANAGEMENT, LP

  • 10% Owner
39,761,797 2017-12-12 3

FLAGSHIP VENTURES FUND V, L.P.

AFEYAN NOUBAR

FLAGSHIP VENTURES FUND V GENERAL PARTNER LLC

  • 10% Owner
No longer subject to file 2017-12-12 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed
Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

SATO VICKI L - Director

2021-07-23 17:33:07 -0400 2021-07-21 S 866 $65.24 d 133,231 direct yes

SATO VICKI L - Director

2021-07-23 17:33:07 -0400 2021-07-21 S 400 $64.25 d 134,097 direct yes

SATO VICKI L - Director

2021-07-23 17:33:07 -0400 2021-07-21 S 400 $65.78 d 132,831 direct yes

SCHUTH ALEXANDER O. - Officer COO AND SECRETARY see footnote

2021-07-08 16:06:31 -0400 2021-07-06 S 10,000 $76.20 d 491,582 indirect yes -3.7514 -10.7835 0.0 1 -11.4618 4

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-07-06 16:14:11 -0400 2021-07-01 S 2,459 $77.84 d 2,192,409 indirect yes -2.7687 -16.074 0.0 1 -16.074 6

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-07-06 16:14:11 -0400 2021-07-01 S 12,844 $77.35 d 2,194,868 indirect yes -2.7687 -16.074 0.0 1 -16.074 6

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-07-06 16:14:11 -0400 2021-07-01 S 3,030 $76.38 d 2,207,712 indirect yes -2.7687 -16.074 0.0 1 -16.074 6

SATO VICKI L - Director

2021-06-24 16:51:49 -0400 2021-06-23 S 986 $71.11 d 134,497 direct yes 0.4954 3.1066 5.0348 4 0.0 1

SATO VICKI L - Director

2021-06-24 16:51:49 -0400 2021-06-23 S 680 $70.20 d 135,483 direct yes 0.4954 3.1066 5.0348 4 0.0 1

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 M 39,303 d 7,862 direct

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 M 27,245 $19.50 a 2,638,748 direct 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 M 27,245 d 0 direct

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 S 700 $71.06 d 2,544,370 direct yes 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 M 27,830 $18.92 a 2,611,503 direct 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 M 27,830 d 0 direct

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 S 93,678 $70.35 d 2,545,070 direct yes 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

TESSIER-LAVIGNE MARC - Director

2021-06-08 17:10:48 -0400 2021-06-07 M 39,303 $18.00 a 2,583,673 direct 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

SCHUTH ALEXANDER O. - Officer COO AND SECRETARY see footnote

2021-06-08 17:10:20 -0400 2021-06-04 S 5,660 $64.35 d 505,922 indirect yes 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

SCHUTH ALEXANDER O. - Officer COO AND SECRETARY see footnote

2021-06-08 17:10:20 -0400 2021-06-04 S 4,340 $64.82 d 501,582 indirect yes 2.3586 1.531 -10.9793 8.1931 16 -11.7793 25

SCHENKEIN DAVID P - Director

2021-06-04 18:37:06 -0400 2021-06-02 A 6,222 a 6,222 direct

TESSIER-LAVIGNE MARC - Director

2021-06-04 18:37:56 -0400 2021-06-02 A 2,074 a 2,544,370 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

KLEIN PETER S - Director

2021-06-04 18:34:41 -0400 2021-06-02 A 6,222 a 6,222 direct

NELSEN ROBERT - Director

2021-06-04 18:35:30 -0400 2021-06-02 A 2,074 a 12,432 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

COOK JENNIFER E. - Director

2021-06-04 18:32:32 -0400 2021-06-02 A 6,222 a 6,222 direct

SATO VICKI L - Director

2021-06-04 18:36:17 -0400 2021-06-02 A 6,222 a 6,222 direct

SCHENKEIN DAVID P - Director

2021-06-04 18:37:06 -0400 2021-06-02 A 2,074 a 5,327 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

FLATLEY JAY T - Director

2021-06-04 18:33:35 -0400 2021-06-02 A 6,222 a 6,222 direct

KLEIN PETER S - Director

2021-06-04 18:34:41 -0400 2021-06-02 A 2,074 a 5,327 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

COLE DOUGLAS G. - Director

2021-06-04 18:31:25 -0400 2021-06-02 A 6,222 a 6,222 direct

COOK JENNIFER E. - Director

2021-06-04 18:32:32 -0400 2021-06-02 A 2,074 a 5,327 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

SATO VICKI L - Director

2021-06-04 18:36:17 -0400 2021-06-02 A 2,074 a 136,163 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

TESSIER-LAVIGNE MARC - Director

2021-06-04 18:37:56 -0400 2021-06-02 A 6,222 a 6,222 direct

FLATLEY JAY T - Director see footnote

2021-06-04 18:33:35 -0400 2021-06-02 A 2,074 a 330,327 indirect 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

NELSEN ROBERT - Director

2021-06-04 18:35:30 -0400 2021-06-02 A 6,222 a 6,222 direct

COLE DOUGLAS G. - Director

2021-06-04 18:31:25 -0400 2021-06-02 A 2,074 a 5,327 direct 1.2528 4.4822 -9.7996 9.1871 18 -10.9688 27

NELSEN ROBERT - Director

2021-06-03 20:55:40 -0400 2021-06-01 M 3,253 a 10,358 direct 11.1386 16.0272 0.0464 21.349 19 -1.052 28

FLATLEY JAY T - Director

2021-06-03 20:53:32 -0400 2021-06-01 M 3,253 d 0 direct

KLEIN PETER S - Director

2021-06-03 20:54:38 -0400 2021-06-01 M 3,253 a 3,253 direct 11.1386 16.0272 0.0464 21.349 19 -1.052 28

COOK JENNIFER E. - Director

2021-06-03 20:52:37 -0400 2021-06-01 M 3,253 d 0 direct

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-06-03 20:08:23 -0400 2021-06-01 S 2,102 $62.76 d 2,211,096 indirect yes 11.1386 16.0272 0.0464 21.349 19 -1.052 28

SCHENKEIN DAVID P - Director

2021-06-03 20:57:14 -0400 2021-06-01 M 3,253 d 0 direct

FLATLEY JAY T - Director see footnote

2021-06-03 20:53:32 -0400 2021-06-01 M 3,253 a 328,253 indirect 11.1386 16.0272 0.0464 21.349 19 -1.052 28

COLE DOUGLAS G. - Director

2021-06-03 20:51:25 -0400 2021-06-01 M 3,253 d 0 direct

COOK JENNIFER E. - Director

2021-06-03 20:52:37 -0400 2021-06-01 M 3,253 a 3,253 direct 11.1386 16.0272 0.0464 21.349 19 -1.052 28

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-06-03 20:08:23 -0400 2021-06-01 S 2,750 $62.09 d 2,213,198 indirect yes 11.1386 16.0272 0.0464 21.349 19 -1.052 28

NELSEN ROBERT - Director

2021-06-03 20:55:40 -0400 2021-06-01 M 3,253 d 0 direct

SCHENKEIN DAVID P - Director

2021-06-03 20:57:14 -0400 2021-06-01 M 3,253 a 3,253 direct 11.1386 16.0272 0.0464 21.349 19 -1.052 28

KLEIN PETER S - Director

2021-06-03 20:54:38 -0400 2021-06-01 M 3,253 d 0 direct

COLE DOUGLAS G. - Director

2021-06-03 20:51:25 -0400 2021-06-01 M 3,253 a 3,253 direct 11.1386 16.0272 0.0464 21.349 19 -1.052 28

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-06-03 20:08:23 -0400 2021-06-01 S 354 $63.50 d 2,210,742 indirect yes 11.1386 16.0272 0.0464 21.349 19 -1.052 28

WATTS RYAN J. - Director - Officer PRESIDENT AND CEO see footnote

2021-06-03 20:08:23 -0400 2021-06-01 S 13,127 $60.98 d 2,215,948 indirect yes 11.1386 16.0272 0.0464 21.349 19 -1.052 28

SATO VICKI L - Director

2021-05-28 16:03:43 -0400 2021-05-26 S 894 $64.90 d 134,861 direct yes 3.5233 18.1036 3.848 27.3583 22 0.0 1

SATO VICKI L - Director

2021-05-28 16:03:43 -0400 2021-05-26 S 40 $66.72 d 134,089 direct yes 3.5233 18.1036 3.848 27.3583 22 0.0 1

SATO VICKI L - Director

2021-05-28 16:03:43 -0400 2021-05-26 S 732 $65.88 d 134,129 direct yes 3.5233 18.1036 3.848 27.3583 22 0.0 1

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

IBR Securities Loan Availability

Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

Security Date/Time Rebate Rate Fee Rate Shares Available
DENALI THERAPEUTICS INC DNLI 2021-07-23 22:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 21:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 21:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 20:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 20:15:05 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 19:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 19:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 18:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 18:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 17:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 17:15:02 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 16:45:02 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 16:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 15:45:02 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 15:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 14:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 14:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 13:45:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 13:15:03 UTC -0.17 0.25 1000000
DENALI THERAPEUTICS INC DNLI 2021-07-23 12:45:03 UTC -0.17 0.25 1000000

Current Active Short Positions

Holder Issuer Net Short Position Position Date Origin
Trust for Professional Managers- Convergence Market Neutral Fund DNLI -2024.0 shares, $-64565.6 2020-08-31 N-PORT
FundVantage Trust- Gotham Enhanced Index Plus Fund DNLI -330.0 shares, $-5778.3 2020-03-31 N-PORT
FundVantage Trust- Gotham Defensive Long Fund DNLI -24.0 shares, $-420.24 2020-03-31 N-PORT
FundVantage Trust- Gotham Index Plus All-Cap Fund DNLI -325.0 shares, $-5690.75 2020-03-31 N-PORT

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