Amicus Therapeutics Inc (FOLD)

HEALTH CARE: PHARMACEUTICALS
SIC: PHARMACEUTICAL PREPARATIONS

1 CEDAR BROOK DRIVE CRANBURY, NJ 08512

Amicus Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of small molecule, orally-administered drugs, known as pharmacological chaperones, for the treatment of a range of human genetic diseases. The pharmacological chaperone technology involves the use of small molecules to restore biological activity in cells by binding to a misfolded protein caused by a genetic mutation. The company is targeting lysosomal storage disorders, which are severe, chronic genetic diseases with unmet medical needs. Its lead compound includes Amigal, which is in Phase II clinical trials is used for the treatment of Fabry disease that causes kidney failure, cardiac abnormalities, and neurological complications. The company is also developing AT2101 for the treatment of Gaucher disease, which causes an enlarged liver and spleen, low levels of red blood cells and platelets, bone pain, and fractures; and AT2220 for the treatment of Pompe disease, which causes muscle weakness primarily affecting breathing, mobility, and heart function. The company has a strategic collaboration with Shire Human Genetic Therapies, Inc. to jointly develop pharmacological chaperone compounds for lysosomal storage disorders.

Data as of 2020-09-12
Market Cap3.336 Billion Shares Outstanding258.788 Million Avg 30-day Volume1.575 Million
P/E Ratio Dividend Yield EPS-1.14
Price/Sales14.699 Price cash flow ratio Price free cash flow ratio-12.3
Book Value1.39 Price to Tangible Book23.8 Alpha0.0
Short Interest Ratio % Short Interest to Float R-squared0.091219
BETA1.17512 52-week High/Low16.13 / 6.25 Stddev0.166245
View SEC Filings from FOLD instead.
Q2 2020 All 13F Filers Prior Change Hedge Funds 1 Prior Change
In top 10: 7 6 16.67% 5 (0.33%) 4 (0.26%) 25.0%
Funds Holding: 224 202 10.89% 73 (4.76%) 65 (4.16%) 12.31%
13F shares: 277.401 Million 279.74 Million -0.84% 122.921 Million 124.382 Million -1.17%
% Ownership 47.7059 48.2976 -1.23%
New Positions: 43 30 43.33% 18 15 20.0%
Increased Positions 71 66 7.58% 21 18 16.67%
Closed Positions 17 50 -66.0% 9 24 -62.5%
Reduced Positions 74 72 2.78% 25 25 0.0%
Total Calls 2.878 Million 1.446 Million 99.06% 352.1 Thousand 202.5 Thousand 73.88%
Total Puts 269.501 Thousand 433.375 Thousand -37.81% 114.7 Thousand 121.8 Thousand -5.83%
PUT/CALL Ratio 0.09 0.3 -70.0% 0.33 0.6 -45.0%
1 hedge funds and active managers as identified by whalewisdom.com through public filings.

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Funds Holding FOLD (via 13F filings)

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*Please note that if a filer hasn't submitted a 13F filing for a quarter then the filer's shares will be listed as "Sold All"

Mutual Funds Holding FOLD BETA

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Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

3 Thousand total shares from 2 transactions

Open Market Sells (S)

158.5 Thousand total shares from 7 transactions

Exercise Derivative Conversion (M)

128.9 Thousand total shares from 7 transactions

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

CROWLEY JOHN F CHAIRMAN & CEO

  • Officer
  • Director
915,708 2020-09-01 25

WHITMAN BURKE W

  • Director
33,967 2020-09-01 5

BARTH JAY CHIEF MEDICAL OFFICER

  • Officer
163,224 2020-08-31 12

PROUT SAMANTHA PRINCIPAL ACCOUNTING OFFICER

  • Officer
17,135 2020-08-05 6

CAMPBELL BRADLEY L CHIEF OPERATING OFFICER

  • Officer
  • Director
338,764 2020-08-03 19

ROSENBERG ELLEN CHIEF LEGAL OFFICER

  • Officer
210,169 2020-07-16 7

QUIMI DAPHNE CHIEF FINANCIAL OFFICER

  • Officer
207,179 2020-07-01 7

DO HUNG CHIEF SCIENCE OFFICER

  • Officer
520,807 2020-06-15 6

MCGLYNN MARGARET G

  • Director
27,919 2020-06-04 3

RAAB MICHAEL

  • Director
21,000 2020-06-04 2

SBLENDORIO GLENN

  • Director
33,933 2020-06-04 1

LOVE TED W

  • Director
131,000 2020-06-04 1

ESSNER ROBERT

  • Director
21,000 2020-06-04 1

WHEELER CRAIG A

  • Director
21,000 2020-06-04 1

BLEIL LYNN DORSEY

  • Director
21,705 2020-06-04 1

CLARK DAVID MICHAEL CHIEF PEOPLE OFFICER

  • Officer
146,621 2020-02-12 3

PERCEPTIVE ADVISORS LLC

PERCEPTIVE LIFE SCIENCES MASTER FUND LTD

EDELMAN JOSEPH

  • 10% Owner
20,724,424 2019-02-12 0

BAIRD WILLIAM D III CHIEF FINANCIAL OFFICER

  • Officer
117,622 2018-10-15 0

ANDREWS KURT J. SVP, HUMAN RESOURCES

  • Officer
35,469 2018-07-02 0

HAYDEN DONALD J JR

  • Director
8,895 2018-06-07 0

BARER SOL J

  • Director
0 2016-06-09 0

REDMILE GROUP, LLC

GREEN JEREMY

  • 10% Owner
12,890,146 2016-06-03 0

PEIST KENNETH VP, LEGAL & IP

  • Officer
18,874 2016-01-04 0

VALENZANO KEN SVP, PHARMACOLOGY & BIOLOGY

  • Officer
27,687 2015-07-13 0

DOSHI DIPAL SVP STRATEGY & BUS DEV

  • Officer
1,706 2015-07-07 0

GERSHKOWITZ JAYNE SVP, CHIEF PATIENT ADVOCATE

  • Officer
5,693 2015-07-01 0

CASTELLI JEFF SVP, PROGRAM MANAGEMENT

  • Officer
25,000 2015-06-22 0

DILONE ENRIQUE SVP, TECHNICAL OPERATIONS

  • Officer
30,688 2015-06-19 0

YU JULIE VP CLINICAL OPS & DATA MGMT

  • Officer
0 2015-06-15 0

KIRK JOHN VP, REGULATORY AFFAIRS

  • Officer
0 2015-06-01 0

BALDRY MARK VP GLOBAL MARKETING

  • Officer
25,000 2015-06-01 0

DAVID ALLSOP SVP INTERNATIONAL

  • Officer
0 2015-04-27 0

GLAXOSMITHKLINE PLC

  • FORMER 10% OWNER (1)
No longer subject to file 2014-10-27 0

BARRETT M JAMES

  • Director
  • 10% Owner
0 2014-06-12 0

TOPPER JAMES N

  • Director
0 2014-06-12 0

LOCKHART DAVID J CHIEF SCIENTIFIC OFFICER

  • Officer
0 2013-06-18 0

WINTERBOTTOM JOAN SVP, HUMAN RESOURCES

  • Officer
0 2013-06-18 0

MACALUSO PETER M VP & CORPORATE COUNSEL

  • Officer
0 2013-06-18 0

WINKLER ROBERT E VP, CLIN RESEARCH & OPERATIONS

  • Officer
0 2012-06-04 0

BOUDES POL F CHIEF MEDICAL OFFICER

  • Officer
0 2012-06-04 0

GILMORE GEOFFREY SVP & GENERAL COUNSEL

  • Officer
0 2012-03-12 0

BARRIS PETER J

  • 10% Owner
5,650,340 2012-03-07 0

KRAMLICH C RICHARD

  • 10% Owner
5,650,340 2012-03-07 0

NEWHALL CHARLES W III

  • 10% Owner
5,650,340 2012-03-07 0

PERRY MARK W

  • 10% Owner
5,650,340 2012-03-07 0

NEW ENTERPRISE ASSOCIATES 11 LP

NEA PARTNERS 11 LP

NEA 11 GP, LLC

BASKETT FOREST

DRANT RYAN D

KOLLURI KRISHNA KITTU

SANDELL SCOTT D

  • 10% Owner
4,584,311 2012-03-07 0

SCHAEFFER ORLOV S NICOLE SVP, HR & LEADERSHIP DEVT

  • Officer
0 2012-02-15 0

BARKAS ALEXANDER E

  • Director
0 2011-05-24 0

PATTERSON MATTHEW R ACTING CEO & PRESIDENT

  • Officer
106,547 2011-04-18 0

NEFF P SHERRILL

  • Director
0 2010-06-15 0

JOHN MCADAM M VP, FINANCE & ACCOUNTING

  • Officer
0 2010-06-15 0

DENTZER JAMES E CHIEF FINANCIAL OFFICER

  • Officer
32,075 2009-10-01 0

PALLING DAVID SR VP, TECHNICAL OPERATIONS

  • Officer
34,040 2009-06-26 0

BLOCH STEPHEN M

  • Director
1,714,090 2009-02-11 0

LICHOLAI GREGORY P VP, MEDICAL AFFAIRS

  • Officer
0 2009-02-03 0

SHENKER ANDREW VP, CLINICAL RESEARCH

  • Officer
0 2009-02-03 0

WEINHOFF GREGORY M

  • Director
2,058,555 2008-08-14 0

FHM IV LP

FRAZIER HEALTHCARE V, LP

FHM V, LP

FHM V, LLC

FRAZIER HEALTHCARE IV LP

FRAZIER AFFILIATES IV LP

  • 10% Owner
915,924 2008-03-06 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed
Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-09-02 16:28:08 -0400 2020-09-01 M 20,000 $5.96 a 880,713 direct 0.4428 -4.8708 2.952 4 -4.8708 6

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-09-02 16:28:08 -0400 2020-09-01 M 20,000 d 43,975 direct

WHITMAN BURKE W - Director

2020-09-02 16:28:59 -0400 2020-09-01 P 1,500 $14.62 a 33,967 direct yes 0.4428 -4.8708 2.952 4 -4.8708 6

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-09-02 16:28:08 -0400 2020-09-01 S 29,900 $14.18 d 850,813 direct yes 0.4428 -4.8708 2.952 4 -4.8708 6

BARTH JAY - Officer CHIEF MEDICAL OFFICER

2020-09-02 16:27:00 -0400 2020-08-31 M 28,750 $6.10 a 191,954 direct 0.4428 -4.8708 2.952 4 -4.8708 6

BARTH JAY - Officer CHIEF MEDICAL OFFICER

2020-09-02 16:27:00 -0400 2020-08-31 M 28,750 d 1,250 direct

BARTH JAY - Officer CHIEF MEDICAL OFFICER

2020-09-02 16:27:00 -0400 2020-08-31 S 28,750 $14.74 d 163,204 direct yes 0.4428 -4.8708 2.952 4 -4.8708 6

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-08-19 16:56:16 -0400 2020-08-17 S 20,000 $14.89 d 860,713 direct yes -0.4093 -2.0464 0.0 1 -3.1378 5

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-08-19 16:56:16 -0400 2020-08-17 M 20,000 $5.13 a 880,713 direct -0.4093 -2.0464 0.0 1 -3.1378 5

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-08-19 16:56:16 -0400 2020-08-17 M 20,000 d 62,485 direct

PROUT SAMANTHA - Officer PRINCIPAL ACCOUNTING OFFICER

2020-08-07 20:04:34 -0400 2020-08-05 S 198 $15.05 d 17,135 direct yes -4.2022 -2.1011 0.0 1 -5.4498 5

PROUT SAMANTHA - Officer PRINCIPAL ACCOUNTING OFFICER

2020-08-07 20:04:34 -0400 2020-08-05 M 198 $10.04 a 17,333 direct -4.2022 -2.1011 0.0 1 -5.4498 5

PROUT SAMANTHA - Officer PRINCIPAL ACCOUNTING OFFICER

2020-08-07 20:04:34 -0400 2020-08-05 M 198 d 5,742 direct

CAMPBELL BRADLEY L - Director - Officer CHIEF OPERATING OFFICER

2020-08-05 16:03:49 -0400 2020-08-03 M 10,000 d 0 direct

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-08-05 16:02:35 -0400 2020-08-03 M 20,000 d 63,975 direct

CAMPBELL BRADLEY L - Director - Officer CHIEF OPERATING OFFICER

2020-08-05 16:03:49 -0400 2020-08-03 S 10,000 $14.78 d 338,764 direct yes 0.3909 -4.3648 -4.886 0.3909 2 -16.0261 26

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-08-05 16:02:35 -0400 2020-08-03 S 39,655 $14.78 d 860,713 direct yes 0.3909 -4.3648 -4.886 0.3909 2 -16.0261 26

WHITMAN BURKE W - Director

2020-08-05 16:05:05 -0400 2020-08-03 P 1,500 $14.53 a 32,467 direct yes 0.3909 -4.3648 -4.886 0.3909 2 -16.0261 26

CAMPBELL BRADLEY L - Director - Officer CHIEF OPERATING OFFICER

2020-08-05 16:03:49 -0400 2020-08-03 M 10,000 $6.06 a 348,764 direct 0.3909 -4.3648 -4.886 0.3909 2 -16.0261 26

CROWLEY JOHN F - Director - Officer CHAIRMAN & CEO

2020-08-05 16:02:35 -0400 2020-08-03 M 20,000 $5.96 a 900,368 direct 0.3909 -4.3648 -4.886 0.3909 2 -16.0261 26

BARTH JAY - Officer CHIEF MEDICAL OFFICER

2020-07-29 21:41:14 -0400 2020-07-27 M 30,000 $6.10 a 193,204 direct -1.5668 4.564 -12.1935 4.9728 7 -12.1935 31

BARTH JAY - Officer CHIEF MEDICAL OFFICER

2020-07-29 21:41:14 -0400 2020-07-27 M 30,000 d 30,000 direct

BARTH JAY - Officer CHIEF MEDICAL OFFICER

2020-07-29 21:41:14 -0400 2020-07-27 S 30,000 $15.05 d 163,204 direct yes -1.5668 4.564 -12.1935 4.9728 7 -12.1935 31

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

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