Alpine Immune Sciences Inc (ALPN)

HEALTH CARE: BIOTECHNOLOGY & LIFE SCIENCES
SIC: PHARMACEUTICAL PREPARATIONS

188 EAST BLAINE ST., SUITE 200 SEATTLE, WA 98102

Alpine Immune Sciences, Inc. (AIS) focuses on developing novel protein-based immunotherapies using its proprietary Variant Ig Domain (vIgD) platform technology. The Company develops TIP technology, based on the vIgD platform, to enhance engineered cellular therapies. AIS offers a platform to interact with multiple targets, including many present in the immune synapse.

Data as of 2021-05-08 11:40:22 -0400
Market Cap286.769 Million Shares Outstanding23.897 Million Avg 30-day Volume75.815 Thousand
P/E Ratio Dividend Yield EPS
Price/Sales Debt to Equity EBITDA
Price to Book Value0.0 Forward PE-9.33 Enterprise Value
Total Cash Current Debt Gross Profit
BETA0.27486 52-week High/Low16.37 / 2.58 Next Earnings Date2021-05-17 Price to Cash FLow (P/CF) -9999999.0
Data provided by IEX Cloud
View SEC Filings from ALPN instead.
Q4 2020 All 13F Filers Prior Change Hedge Funds 1 Prior Change
In top 10: 0 1 -100.0% 0 (0.0%) 1 (0.06%) -100.0%
Funds Holding: 45 36 25.0% 25 (1.5%) 18 (1.12%) 38.89%
13F shares: 13.156 Million 12.581 Million 4.57% 11.513 Million 11.322 Million 1.69%
% Ownership 55.2679 52.8544 4.57% 48.3682 47.5638 1.69%
New Positions: 11 17 -35.29% 7 9 -22.22%
Increased Positions 13 10 30.0% 6 4 50.0%
Closed Positions 2 4 -50.0% 2
Reduced Positions 8 3 166.67% 5 1 400.0%
Total Calls
Total Puts
PUT/CALL Ratio
1 hedge funds and active managers as identified by whalewisdom.com through public filings.

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Funds Holding ALPN (via 13F filings)

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*Shares are split adjusted
*Please note that if a filer hasn't submitted a 13F filing for a quarter then the filer's shares will be listed as "Sold All"

Mutual Funds Holding ALPN BETA

Active Schedule 13D and 13G filings

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Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

none

Open Market Sells (S)

20 Thousand total shares from 2 transactions

Exercise Derivative Conversion (M)

15.3 Thousand total shares from 2 transactions

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

GOLD MITCHELL EXECUTIVE CHAIRMAN AND CEO

  • Officer
  • Director
  • 10% Owner
3,251,019 2021-04-13 7

VENKATESAN JAY

  • Director
  • 10% Owner
3,256,309 2021-03-30 3

PENG STANFORD L SEE REMARKS

  • Officer
0 2021-01-05 4

RICKEY JAMES PAUL SENIOR VP AND CFO

  • Officer
0 2021-01-05 3

CONWAY ROBERT E

  • Director
0 2021-01-04 2

TOPPER JAMES N

  • Director
  • 10% Owner
0 2021-01-04 1

THOMPSON PETER A.

  • Director
  • 10% Owner
0 2021-01-04 2

PEETZ CHRISTOPHER

  • Director
0 2021-01-04 1

CUI XIANGMIN

  • Director
  • 10% Owner
0 2021-01-04 1

HERNDAY NATASHA

  • Director
0 2021-01-04 3

ORBIMED ADVISORS LLC

ORBIMED CAPITAL GP VI LLC

  • Director
  • 10% Owner
3,070,955 2020-12-28 1

ALPINE IMMUNOSCIENCES, L.P.

ALPINE BIOVENTURES, GP, LLC

  • 10% Owner
3,000,980 2020-12-22 1

SEKHRI PAUL J

  • Director
0 2020-01-02 0

TIGER MANAGEMENT L.L.C.

  • 10% Owner
137,728 2019-02-08 0

LITTON MARK JAMES SEE REMARKS

  • Officer
0 2019-02-06 0

FRAZIER LIFE SCIENCES VIII, L.P.

FHM LIFE SCIENCES VIII, L.P.

FHM LIFE SCIENCES VIII, L.L.C.

HERON PATRICK J

  • 10% Owner
2,571,450 2019-01-18 0

DECHENG CAPITAL CHINA LIFE SCIENCES USD FUND III, L.P.

DECHENG CAPITAL MANAGEMENT III (CAYMAN), LLC

  • 10% Owner
3,165,735 2019-01-18 0

ORBIMED ADVISORS LLC

ORBIMED CAPITAL GP VI LLC

ISALY SAMUEL D

  • Director
0 2017-07-24 0

BVF PARTNERS L P/IL

BIOTECHNOLOGY VALUE FUND L P

BIOTECHNOLOGY VALUE FUND II LP

BIOTECHNOLOGY VALUE TRADING FUND OS LP

BVF PARTNERS OS LTD.

BVF INC/IL

LAMPERT MARK N

  • 10% Owner
  • SEE EXPLANATION OF RESPONSESSEE EXPLANATION OF RESPONSESSEE EXPLANATION OF RESPONSESSEE EXPLANATION OF RESPONSES
201,811 2017-06-20 0

TROHA JANICE EXEC VICE PRESIDENT / COO

  • Officer
10,000 2017-05-05 0

CARRUTHERS R MICHAEL INTERIM PRESIDENT / CFO

  • Officer
0 2017-01-12 0

RODMAN DAVID MALCOM EXEC VICE PRESIDENT AND CMO

  • Officer
11,368 2017-01-03 0

SMITH CYNTHIA

  • Director
0 2016-11-01 0

LOH EVAN

  • Director
0 2016-09-12 0

MOORE JOHN R

  • Director
0 2016-09-12 0

FURST HOWARD P.

  • Director
0 2016-09-12 0

CONGLETON JON PRESIDENT AND CEO

  • Officer
  • Director
0 2016-09-12 0

FLYNN JAMES E

DEERFIELD MANAGEMENT CO

  • Director
  • 10% Owner
0 2016-09-12 0

SHOEMAKER STEVEN VP CLINICAL R&D

  • Officer
0 2015-09-11 0

GABRIEL SHERIF VICE PRESIDENT RESEARCH

  • Officer
0 2015-09-11 0

LEFF JONATHAN S

  • Director
0 2015-09-11 0

FLYNN JAMES E

DEERFIELD MGMT L.P.

DEERFIELD MANAGEMENT CO

DEERFIELD SPECIAL SITUATIONS FUND, L.P.

DEERFIELD PRIVATE DESIGN FUND L P

DEERFIELD PRIVATE DESIGN FUND II, L.P.

DEERFIELD PRIVATE DESIGN INTERNATIONAL, L.P.

DEERFIELD PRIVATE DESIGN INTERNATIONAL II, L.P.

  • 10% Owner
  • POSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUP
8,858,583 2015-06-23 0

HADLEY HARBOR MASTER INVESTORS (CAYMAN) L.P.

  • 10% Owner
No longer subject to file 2015-06-22 0

JENNISON GLOBAL HEALTHCARE MASTER FUND, LTD.

  • 10% Owner
No longer subject to file 2015-06-22 0

ESTATE OF ARNOLD H. SNIDER, III

  • 10% Owner
1,557,228 2015-06-22 0

ROCK SPRINGS CAPITAL MANAGEMENT LP

  • 10% Owner
No longer subject to file 2015-06-22 0

HAWKES BAY MASTER INVESTORS (CAYMAN) L.P.

  • 10% Owner
No longer subject to file 2015-06-19 0

FLYNN JAMES E

DEERFIELD MGMT L.P.

DEERFIELD MANAGEMENT CO

DEERFIELD PRIVATE DESIGN FUND L P

DEERFIELD PRIVATE DESIGN INTERNATIONAL, L.P.

DEERFIELD PRIVATE DESIGN FUND II, L.P.

DEERFIELD PRIVATE DESIGN INTERNATIONAL II, LTD.

DEERFIELD SPECIAL SITUATIONS FUND, L.P.

  • 10% Owner
  • POSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUPPOSSIBLE MEMBER OF 10% GROUP
404,022 2015-06-16 0

TIGER PARTNERS LP

TIGER PARTNERS GP, LLC

  • 10% Owner
650,915 2015-06-16 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed
Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

GOLD MITCHELL - Director - Officer - > 10% Owner EXECUTIVE CHAIRMAN AND CEO

2021-04-15 18:09:58 -0400 2021-04-14 S 10,000 $10.52 d 250,039 direct yes -0.3636 9.7273 9.7273 6 -0.3636 2

GOLD MITCHELL - Director - Officer - > 10% Owner EXECUTIVE CHAIRMAN AND CEO

2021-04-15 18:09:58 -0400 2021-04-13 S 10,000 $10.07 d 260,039 direct yes -0.3636 9.7273 9.7273 6 -0.3636 2

VENKATESAN JAY - Director - > 10% Owner

2021-04-23 18:14:07 -0400 2021-03-31 M 7,650 d 0 direct

VENKATESAN JAY - Director - > 10% Owner

2021-04-23 18:14:07 -0400 2021-03-31 M 7,650 $3.62 a 218,063 direct -0.7166 3.5032 5.6529 5 -0.7166 2

VENKATESAN JAY - Director - > 10% Owner

2021-04-23 18:14:07 -0400 2021-03-30 M 7,650 $4.09 a 210,413 direct -0.7166 3.5032 5.6529 5 -0.7166 2

VENKATESAN JAY - Director - > 10% Owner

2021-04-23 18:14:07 -0400 2021-03-30 M 7,650 d 0 direct

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

IBR Securities Loan Availability

Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

Security Date/Time Rebate Rate Fee Rate Shares Available
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 22:15:04 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 21:45:02 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 21:15:02 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 20:45:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 20:15:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 19:45:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 19:15:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 18:45:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 18:15:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 17:45:02 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 17:15:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 16:45:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 16:15:03 UTC -0.4779 0.5279 300000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 15:45:03 UTC -0.4779 0.5279 75000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 15:15:03 UTC -0.4779 0.5279 65000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 14:45:04 UTC -0.4779 0.5279 65000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 14:15:04 UTC -0.4779 0.5279 65000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 13:45:04 UTC -0.4779 0.5279 65000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 13:15:03 UTC -0.4779 0.5279 65000
ALPINE IMMUNE SCIENCES INC ALPN 2021-05-10 12:45:02 UTC -0.4779 0.5279 65000

Current Active Short Positions

Holder Issuer Net Short Position Position Date Origin

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