Prelude Therapeutics Inc. (PRLD)

HEALTH CARE: BIOTECHNOLOGY & LIFE SCIENCES
SIC: PHARMACEUTICAL PREPARATIONS

200 POWDER MILL ROAD WILMINGTON, DE 19803

Prelude Therapeutics is a clinical-stage precision oncology company developing innovative drug candidates targeting critical cancer cell pathways. The Company’s lead product candidates are designed to be oral, potent, and selective inhibitors of PRMT5. Prelude’s first clinical candidate, PRT543, is in Phase 1 development for advanced solid tumors and select myeloid malignancies. Prelude is also advancing PRT811, a second PRMT5 inhibitor optimized for high brain exposure, in a Phase 1 clinical trial including glioblastoma multiforme (GBM). The Company’s pipeline also includes its third clinical candidate, PRT1419, an orally available MCL1 inhibitor in Phase 1 development for patients with relapsed/refractory hematologic malignancies, and its two most advanced preclinical candidates, PRT2527, a CDK9 inhibitor, and PRT-SCA2, a SMARCA2 protein degrader.

Data as of 2021-09-19 13:30:29 -0400
Market Cap1.658 Billion Shares Outstanding47.094 Million Avg 30-day Volume300.029 Thousand
P/E Ratio Dividend Yield EPS
Price/Sales Debt to Equity EBITDA
Price to Book Value0.0 Forward PE-15.0 Enterprise Value
Total Cash Current Debt Gross Profit
BETA0.0 52-week High/Low95.38 / 23.69 Next Earnings Date2021-11-09 Price to Cash FLow (P/CF) -50.0359
Data provided by IEX Cloud
View SEC Filings from PRLD instead.

View recent insider trading info

Funds Holding PRLD (via 13F filings)

Refresh Download CSV Download Excel (.xlsx) Download TSV
Filter by:
to
to
to
Refresh
*Shares are split adjusted
*Please note that if a filer hasn't submitted a 13F filing for a quarter then the filer's shares will be listed as "Sold All"

Mutual Funds Holding PRLD BETA

Active Schedule 13D and 13G filings

Please sign in first

Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

none

Open Market Sells (S)

65.3 Thousand total shares from 18 transactions

Exercise Derivative Conversion (M)

65.3 Thousand total shares from 8 transactions

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

MAURO DAVID J CHIEF MEDICAL OFFICER

  • Officer
167,610 2021-09-07 10

PIERCE CHRISTOPHER EVP AND CHIEF OF BUSINESS OPER

  • Officer
211,546 2021-09-02 6

SCHERLE PEGGY CHIEF SCIENTIFIC OFFICER

  • Officer
405,890 2021-08-26 7

PIPER BRIAN CHIEF FINANCIAL OFFICER

  • Officer
264,329 2021-08-25 3

MOROSINI DEBORAH EVP, CHIEF OF CLINICAL AFFAIRS

  • Officer
85,000 2021-07-20 5

VADDI KRISHNA PRESIDENT, CEO

  • Officer
  • Director
285,800 2021-07-20 2

COMBS ANDREW EVP, HEAD OF CHEMISTRY

  • Officer
95,000 2021-07-20 2

BABLER MARTIN

  • Director
0 2021-07-19 2

BAKER BROS. ADVISORS LP

667, L.P.

BAKER BROS. ADVISORS (GP) LLC

BAKER BROTHERS LIFE SCIENCES LP

BAKER FELIX

BAKER JULIAN

  • Director
  • 10% Owner
23,344 2021-06-18 2

FRIEDMAN PAUL A

  • Director
23,344 2021-06-18 1

BONITA DAVID P

  • Director
  • 10% Owner
23,344 2021-06-18 2

DIER MARDI

  • Director
23,344 2021-06-18 2

SANDOR VICTOR

  • Director
23,344 2021-06-18 1

ORBIMED ADVISORS LLC

ORBIMED CAPITAL GP VI LLC

ORBIMED CAPITAL LLC

  • Director
  • 10% Owner
0 2021-01-11 1

ORBIMED ADVISORS LLC

ORBIMED CAPITAL GP VI LLC

  • Director
  • 10% Owner
206,912 2020-09-24 1

NEU KELVIN

  • Director
0 2020-09-24 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed
Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-09-09 16:53:43 -0400 2021-09-07 S 4,640 $37.79 d 0 direct yes -2.4977 7.219 7.219 6 -2.4977 2

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-09-09 16:53:43 -0400 2021-09-07 M 15,000 $1.89 a 15,000 direct -2.4977 7.219 7.219 6 -2.4977 2

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-09-09 16:53:43 -0400 2021-09-07 S 2,873 $36.92 d 4,640 direct yes -2.4977 7.219 7.219 6 -2.4977 2

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-09-09 16:53:43 -0400 2021-09-07 M 15,000 d 167,610 direct

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-09-09 16:53:43 -0400 2021-09-07 S 7,487 $35.91 d 7,513 direct yes -2.4977 7.219 7.219 6 -2.4977 2

PIERCE CHRISTOPHER - Officer EVP AND CHIEF OF BUSINESS OPER

2021-09-07 19:17:05 -0400 2021-09-02 S 6,727 $41.52 d 10,680 direct yes -2.8035 -7.4578 0.0 1 -12.8743 4

PIERCE CHRISTOPHER - Officer EVP AND CHIEF OF BUSINESS OPER

2021-09-07 19:17:05 -0400 2021-09-02 M 17,000 d 207,796 direct

PIERCE CHRISTOPHER - Officer EVP AND CHIEF OF BUSINESS OPER

2021-09-07 19:17:05 -0400 2021-09-02 S 3,343 $40.29 d 17,407 direct yes -2.8035 -7.4578 0.0 1 -12.8743 4

PIERCE CHRISTOPHER - Officer EVP AND CHIEF OF BUSINESS OPER

2021-09-07 19:17:05 -0400 2021-09-02 S 6,930 $42.50 d 3,750 direct yes -2.8035 -7.4578 0.0 1 -12.8743 4

PIERCE CHRISTOPHER - Officer EVP AND CHIEF OF BUSINESS OPER

2021-09-07 19:17:05 -0400 2021-09-02 M 17,000 $12.85 a 20,750 direct -2.8035 -7.4578 0.0 1 -12.8743 4

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-27 M 6,014 d 27,018 direct

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-27 S 2,707 $36.23 d 173,527 direct yes 3.8946 2.942 8.2936 3 0.0 1

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-27 S 2,700 $35.32 d 176,234 direct yes 3.8946 2.942 8.2936 3 0.0 1

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-27 S 607 $37.08 d 172,920 direct yes 3.8946 2.942 8.2936 3 0.0 1

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-27 M 6,014 $1.43 a 178,934 direct 3.8946 2.942 8.2936 3 0.0 1

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-26 S 1,700 $35.19 d 172,920 direct yes 3.8946 2.942 8.2936 3 0.0 1

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-26 M 1,700 d 33,032 direct

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-30 17:16:37 -0400 2021-08-26 M 1,700 $1.43 a 174,620 direct 3.8946 2.942 8.2936 3 0.0 1

PIPER BRIAN - Officer CHIEF FINANCIAL OFFICER

2021-08-27 20:02:38 -0400 2021-08-25 S 2,344 $34.33 d 0 direct yes -3.3315 2.519 4.6858 4 -3.3315 2

PIPER BRIAN - Officer CHIEF FINANCIAL OFFICER

2021-08-27 20:02:38 -0400 2021-08-25 M 8,333 $1.89 a 8,333 direct -3.3315 2.519 4.6858 4 -3.3315 2

PIPER BRIAN - Officer CHIEF FINANCIAL OFFICER

2021-08-27 20:02:38 -0400 2021-08-25 S 3,889 $33.23 d 2,344 direct yes -3.3315 2.519 4.6858 4 -3.3315 2

PIPER BRIAN - Officer CHIEF FINANCIAL OFFICER

2021-08-27 20:02:38 -0400 2021-08-25 M 8,333 d 264,329 direct

PIPER BRIAN - Officer CHIEF FINANCIAL OFFICER

2021-08-27 20:02:38 -0400 2021-08-25 S 2,100 $32.44 d 6,233 direct yes -3.3315 2.519 4.6858 4 -3.3315 2

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-17 16:44:45 -0400 2021-08-13 S 2,286 $35.07 d 172,920 direct yes -4.9851 13.899 13.899 6 -4.9851 2

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-17 16:44:45 -0400 2021-08-13 M 1,728 d 34,732 direct

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-17 16:44:45 -0400 2021-08-13 M 1,728 $1.43 a 175,206 direct -4.9851 13.899 13.899 6 -4.9851 2

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-17 16:44:45 -0400 2021-08-13 M 558 d 42,672 direct

SCHERLE PEGGY - Officer CHIEF SCIENTIFIC OFFICER

2021-08-17 16:44:45 -0400 2021-08-13 M 558 $1.89 a 173,478 direct -4.9851 13.899 13.899 6 -4.9851 2

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-08-09 16:26:33 -0400 2021-08-05 M 15,000 $1.89 a 15,000 direct 6.3204 0.219 6.164 20.9324 18 -9.9499 8

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-08-09 16:26:33 -0400 2021-08-05 M 15,000 d 167,610 direct

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-08-09 16:26:33 -0400 2021-08-05 S 2,063 $31.03 d 6,821 direct yes 6.3204 0.219 6.164 20.9324 18 -9.9499 8

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-08-09 16:26:33 -0400 2021-08-05 S 100 $32.63 d 0 direct yes 6.3204 0.219 6.164 20.9324 18 -9.9499 8

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-08-09 16:26:33 -0400 2021-08-05 S 6,116 $29.93 d 8,884 direct yes 6.3204 0.219 6.164 20.9324 18 -9.9499 8

MAURO DAVID J - Officer CHIEF MEDICAL OFFICER

2021-08-09 16:26:33 -0400 2021-08-05 S 6,721 $32.15 d 100 direct yes 6.3204 0.219 6.164 20.9324 18 -9.9499 8

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

IBR Securities Loan Availability

Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

Security Date/Time Rebate Rate Fee Rate Shares Available
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 22:15:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 21:45:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 21:15:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 20:45:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 20:15:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 19:45:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 19:15:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 18:45:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 18:15:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 17:45:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 17:15:03 UTC -0.8278 0.8978 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 16:45:03 UTC -0.8534 0.9234 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 16:15:03 UTC -0.8534 0.9234 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 15:45:03 UTC -0.8534 0.9234 7000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 15:15:04 UTC -0.8534 0.9234 9000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 14:45:02 UTC -0.926 0.996 9000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 14:15:02 UTC -0.926 0.996 9000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 13:45:02 UTC -0.926 0.996 9000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 13:15:03 UTC -0.926 0.996 9000
PRELUDE THERAPEUTICS INC PRLD 2021-09-24 12:45:03 UTC -0.926 0.996 9000

Current Active Short Positions

Holder Issuer Net Short Position Position Date Origin

Elevate your investments