Syros Pharmaceuticals Inc (SYRS)

HEALTH CARE: PHARMACEUTICALS
SIC: PHARMACEUTICAL PREPARATIONS

35 CAMBRIDGE PARK DRIVE CAMBRIDGE, MA 02140

Syros Pharmaceuticals, Inc. operates as a biopharmaceutical company. The Company focuses on developing treatments for cancer and immune-mediated diseases, as well as building a pipeline of gene control medicines. Syros Pharmaceuticals conducts business worldwide.

Data as of 2021-07-19 09:37:13 -0400
Market Cap291.352 Million Shares Outstanding61.858 Million Avg 30-day Volume1.002 Million
P/E Ratio-3.59517 Dividend Yield EPS-1.61
Price/Sales16.61 Debt to Equity1.74 EBITDA-82.876 Million
Price to Book Value1.94 Forward PE3.89 Enterprise Value109.485 Million
Total Cash222.142 Million Current Debt27.369 Million Gross Profit17.541 Million
BETA1.91973 52-week High/Low15.65 / 4.43 Next Earnings Date2021-08-05 Price to Cash FLow (P/CF) -23.6077
Data provided by IEX Cloud
View SEC Filings from SYRS instead.
Q1 2021 All 13F Filers Prior Change Hedge Funds 1 Prior Change
In top 10: 1 4 -75.0% 0 (0.0%) 2 (0.12%) -100.0%
Funds Holding: 107 102 4.9% 37 (2.17%) 39 (2.26%) -5.13%
13F shares: 63.808 Million 56.584 Million 12.77% 25.198 Million 24.211 Million 4.08%
% Ownership 40.8792 43.0822 -5.11%
New Positions: 17 25 -32.0% 6 14 -57.14%
Increased Positions 44 36 22.22% 12 12 0.0%
Closed Positions 12 16 -25.0% 8 8 0.0%
Reduced Positions 29 29 0.0% 11 10 10.0%
Total Calls 165.616 Thousand 127.494 Thousand 29.9% 60.7 Thousand 29.5 Thousand 105.76%
Total Puts 344.506 Thousand 115.541 Thousand 198.17% 90.8 Thousand 77.4 Thousand 17.31%
PUT/CALL Ratio 2.08 0.91 128.57% 1.5 2.62 -42.75%
1 hedge funds and active managers as identified by whalewisdom.com through public filings.

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Syros Pharmaceuticals Inc YCharts
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SEC Web Site SEC DEF 14A Filings

Funds Holding SYRS (via 13F filings)

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*Please note that if a filer hasn't submitted a 13F filing for a quarter then the filer's shares will be listed as "Sold All"

Mutual Funds Holding SYRS BETA

Active Schedule 13D and 13G filings

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Open Market Buys/Sells Last 60 Days

Open Market Buys (P)

none

Open Market Sells (S)

1.2 Thousand total shares from 1 transactions

Exercise Derivative Conversion (M)

none

Current/Former Insiders

Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

OLSON ERIC R CHIEF SCIENTIFIC OFFICER

  • Officer
 0 2021-07-01 4

FANUCCI MARSHA

  • Director
 17,500 2021-06-08 1

SHARP PHILLIP A

  • Director
 17,500 2021-06-08 1

YOUNG RICHARD A

  • Director
 17,500 2021-06-08 9

NASHAT AMIR

  • Director
 17,500 2021-06-08 1

WIRTH PETER

  • Director
 17,500 2021-06-08 1

AKKARAJU SRINIVAS

  • Director
 17,500 2021-06-08 3

ALLES MARK J

  • Director
 17,500 2021-06-08 1

ECKHARDT SUE GAIL

  • Director
 17,500 2021-06-08 3

STEPHENS KRISTIN CHIEF DEVELOPMENT OFFICER

  • Officer
 45,000 2021-06-08 1

SIMONIAN NANCY A PRESIDENT & CEO

  • Officer
  • Director
 0 2021-02-17 2

ROTH DAVID CHIEF MEDICAL OFFICER

  • Officer
 0 2021-02-17 1

QUIRK GERALD E CHIEF LEGAL & ADMIN. OFFICER

  • Officer
 0 2021-02-17 1

SPRINGHORN JEREMY P. CHIEF BUSINESS OFFICER

  • Officer
 0 2021-02-17 1

FERRA JOSEPH J JR CHIEF FINANCIAL OFFICER

  • Officer
 0 2021-02-17 1

ARCH VENTURE FUND VII, L.P.

ARCH VENTURE PARTNERS VII, L.P.

ARCH VENTURE PARTNERS VII, LLC

CRANDELL KEITH

BYBEE CLINTON

NELSEN ROBERT

  • 10% Owner
 No longer subject to file 2019-07-15 0

SATO VICKI L

  • Director
 0 2019-06-11 0

BONNEY MICHAEL W

  • Director
 0 2019-06-11 0

SHAW ALICE TSANG

  • Director
 0 2019-06-11 0

AFEYAN NOUBAR

  • 10% Owner
 0 2017-12-31 0

DESIMONE COLLEEN ELIZABETH PRINCIPAL ACCOUNTING OFFICER

  • Officer
 0 2017-10-23 0

FLAGSHIP VENTURES FUND IV, L.P.

FLAGSHIP VENTURES FUND IV-RX, L.P.

FLAGSHIP VENTURELABS IV, LLC

FLAGSHIP VENTURES FUND IV GENERAL PARTNER LLC

AFEYAN NOUBAR

KANIA EDWIN M JR

  • 10% Owner
 3,253,491 2017-08-17 0

NELSEN ROBERT

  • Director
  • 10% Owner
 0 2017-06-08 0

PATEL SANJ K

  • Director
 0 2017-06-08 0

KUVALANKA KYLE D. CHIEF OPERATING OFFICER

  • Officer
 0 2017-02-10 0

BANCEL STEPHANE

  • Director
 0 2016-09-15 0

WUXI PHARMTECH HEALTHCARE FUND I L.P.

  • 10% Owner
 No longer subject to file 2016-07-06 0

ARCH VENTURE FUND VII LP

ARCH VENTURE PARTNERS VII, L.P.

ARCH VENTURE PARTNERS VII, LLC

CRANDELL KEITH

BYBEE CLINTON

  • 10% Owner
 4,637,137 2016-07-06 0

WUXI HEALTHCARE VENTURES II, L.P.

  • 10% Owner
 No longer subject to file 2016-07-06 0

POLARIS MANAGEMENT CO. VII, L.L.C.

POLARIS PARTNERS VII, L.P.

POLARIS ENTREPRENEURS' FUND VII, L.P.

  • 10% Owner
 No longer subject to file 2016-07-06 0

REDMILE GROUP, LLC

GREEN JEREMY

  • 10% Owner
 No longer subject to file 2016-07-06 0

FLYNN JAMES E

DEERFIELD MGMT L.P.

DEERFIELD MANAGEMENT CO

DEERFIELD SPECIAL SITUATIONS FUND, L.P.

DEERFIELD MGMT III, L.P.

DEERFIELD PRIVATE DESIGN FUND III, L.P.

  • 10% Owner
  • POSSIBLE MEMBERS OF 10% GROUPPOSSIBLE MEMBERS OF 10% GROUPPOSSIBLE MEMBERS OF 10% GROUPPOSSIBLE MEMBERS OF 10% GROUPPOSSIBLE MEMBERS OF 10% GROUPPOSSIBLE MEMBERS OF 10% GROUP
 3,790,440 2016-07-06 0

AISLING CAPITAL III LP

AISLING CAPITAL PARTNERS III LP

AISLING CAPITAL PARTNERS III LLC

ELMS STEVE

SCHIFF ANDREW N

PURCELL DENNIS J

  • 10% Owner
 No longer subject to file 2016-07-06 0

GRAY NATHANAEL

  • 10% Owner
 426,666 2016-06-29 0

CONDE JORGE CHIEF STRATEGY OFFICER

  • Officer
 0 2016-06-29 0

JEB SYROS TRUST

  • 10% Owner
 351,666 2016-06-29 0

PERSPECTA TRUST LLC

  • 10% Owner
 351,666 2016-06-29 0

Insider Transactions Last 60 Days

Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
Disposed		 Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days

OLSON ERIC R - Officer CHIEF SCIENTIFIC OFFICER

2021-07-01 17:20:52 -0400 2021-07-01 S 1,164 $5.55 d 0 direct yes -1.8553 -2.5974 0.0 1 -5.0093 3

ALLES MARK J - Director

2021-06-10 17:24:59 -0400 2021-06-08 A 17,500 a 17,500 direct

YOUNG RICHARD A - Director

2021-06-10 17:31:28 -0400 2021-06-08 A 17,500 a 17,500 direct

NASHAT AMIR - Director

2021-06-10 17:29:11 -0400 2021-06-08 A 17,500 a 17,500 direct

AKKARAJU SRINIVAS - Director

2021-06-10 17:39:48 -0400 2021-06-08 A 17,500 a 17,500 direct

ECKHARDT SUE GAIL - Director

2021-06-10 17:27:47 -0400 2021-06-08 A 17,500 a 17,500 direct

SHARP PHILLIP A - Director

2021-06-10 17:30:04 -0400 2021-06-08 A 17,500 a 17,500 direct

WIRTH PETER - Director

2021-06-10 17:30:48 -0400 2021-06-08 A 17,500 a 17,500 direct

FANUCCI MARSHA - Director

2021-06-10 17:28:20 -0400 2021-06-08 A 17,500 a 17,500 direct

* -

Transaction Code Definitions
Code Definition
A Grant, award or other acquisition pursuant to Rule 16b-3(d)
C Conversion of derivative security
D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
E Expiration of short derivative position
F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
G Bona fide gift
H Expiration (or cancellation) of long derivative position with value received
I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
J Other acquisition or disposition
L Small acquisition under Rule 16a-6
M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
O Exercise of out-of-the-money derivative security
P Open market or private purchase of non-derivative or derivative security
S Open market or private sale of non-derivative or derivative security
U Disposition pursuant to a tender of shares in a change of control transaction
W Acquisition or disposition by will or the laws of descent and distribution
X Exercise of in-the-money or at-the-money derivative security
Z Deposit into or withdrawal from voting trust

IBR Securities Loan Availability

Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

Security Date/Time Rebate Rate Fee Rate Shares Available
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 22:15:03 UTC -0.2904 0.3704 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 21:45:03 UTC -0.2886 0.3686 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 21:15:03 UTC -0.2886 0.3686 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 20:45:03 UTC -0.2847 0.3647 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 20:15:05 UTC -0.2847 0.3647 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 19:45:03 UTC -0.2847 0.3647 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 19:15:03 UTC -0.2847 0.3647 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 18:45:03 UTC -0.2771 0.3571 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 18:15:03 UTC -0.2771 0.3571 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 17:45:03 UTC -0.2771 0.3571 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 17:15:02 UTC -0.2771 0.3571 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 16:45:02 UTC -0.2754 0.3554 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 16:15:03 UTC -0.2754 0.3554 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 15:45:02 UTC -0.2754 0.3554 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 15:15:03 UTC -0.2754 0.3554 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 14:45:03 UTC -0.17 0.25 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 14:15:03 UTC -0.17 0.25 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 13:45:03 UTC -0.17 0.25 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 13:15:03 UTC -0.17 0.25 650000
SYROS PHARMACEUTICALS INC SYRS 2021-07-23 12:45:03 UTC -0.17 0.25 800000

Current Active Short Positions

Holder Issuer Net Short Position Position Date Origin

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