Synthorx Inc (THOR)

Sector:
HEALTH CARE
Industry:
BIOTECHNOLOGY & LIFE SCIENCES
SIC:
PHARMACEUTICAL PREPARATIONS
CEO:
Laura Shawver
Employees:
38
11099 NORTH TORREY PINES ROAD, SUITE 190, LA JOLLA, CA 92037
(858) 750-4700

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Synthorx, Inc., a biopharmaceutical company, focuses on the development of cytokine Synthorin programs for the treatment of cancer and autoimmune disorders in the United States. The company's lead product candidate is THOR-707, a variant of recombinant human IL-2 that is in the development in various solid tumor types as a single agent and in combination with an immune checkpoint inhibitor. It also develops IL-2 Synthorin for autoimmune indications; IL-10 Synthorin, a naturally occurring immune cell growth factor in humans for the treatment of immuno-oncology (IO); and IL-15 Synthorins, an immunoregulatory cytokine to treat IO. In addition, the company develops other Synthorin programs targeting undisclosed cytokines that play critical roles in the orchestration of anti-tumor responses by innate and adaptive immune cells. The company was formerly known as Alinos, Inc. and changed its name to Synthorx, Inc. in March 2014. Synthorx, Inc. was founded in 2014 and is headquartered in La Jolla, California.

Data derived from most recent annual or quarterly report
Market Cap 2.194 Billion Shares Outstanding32.27 Million Avg 30-day Volume 508.822 Thousand
P/E Ratio0.0 Dividend Yield0.0 EPS-0.38
Price to Revenue0.0 Debt to Equity0.0 EBITDA0
Price to Book Value3.4623 Operating Margin0.0 Enterprise Value375.25 Million
Current Ratio18.866 EPS Growth0 Quick Ratio18.055
1 Yr BETA 1.2374 52-week High/Low 0.0 / Profit Margin0.0
Operating Cash Flow Growth0.0 Altman Z-Score27.1601 Free Cash Flow to Firm 0

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Recent Filings

Financial Reporting

Events (8k)

  • 8-K: filed on 2019-12-09:
    Item 1.01: Entry into a Material Definitive Agreement
    Item 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
    Item 8.01: Other Events
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2019-11-08:
    Item 9.01: Financial Statements and Exhibits
    Item 8.01: Other Events
  • 8-K: filed on 2019-11-08:
    Item 9.01: Financial Statements and Exhibits
    Item 8.01: Other Events
  • 8-K: filed on 2019-09-16:
    Item 9.01: Financial Statements and Exhibits
    Item 8.01: Other Events
  • 8-K: filed on 2019-09-13:
    Item 5.02: Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers
  • 8-K: filed on 2019-06-20:
    Item 8.01: Other Events
  • 8-K: filed on 2019-06-10:
    Item 5.07: Submission of Matters to a Vote of Security Holders
  • 8-K: filed on 2019-05-31:
    Item 7.01: Regulation FD Disclosure
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2019-04-30:
    Item 2.02: Results of Operations and Financial Condition
    Item 9.01: Financial Statements and Exhibits
  • 8-K: filed on 2019-04-02:
    Item 7.01: Regulation FD Disclosure
    Item 9.01: Financial Statements and Exhibits
  • Proposed Sales (Form 144)

    Proxy

    Prospectus

    All

    Open Market Buys/Sells Last 60 Days

    Open Market Buys (P)

    none

    Open Market Sells (S)

    none

    Exercise Derivative Conversion (M)

    none

    Current/Former Insiders

    Insider Name Type Last Reported Shares Held Last Reported Date Filings in past year

    CAPPS VICKIE L

    • Director
    No longer subject to file 2020-01-23 0

    POWELL ANDREW KENNETH WILLIAM

    • Director
    No longer subject to file 2020-01-23 0

    RA CAPITAL MANAGEMENT, L.P.

    RA CAPITAL HEALTHCARE FUND LP

    SHAH RAJEEV M.

    • 10% Owner
    0 2020-01-23 0

    THOMPSON PETER A.

    • Director
    • 10% Owner
    No longer subject to file 2020-01-23 0

    LICHTER JAY

    • Director
    No longer subject to file 2020-01-23 0

    KOLCHINSKY PETER

    • Director
    • 10% Owner
    No longer subject to file 2020-01-23 0

    SHAWVER LAURA PRESIDENT AND CEO

    • Officer
    • Director
    No longer subject to file 2020-01-23 0

    SHAH PRATIK

    • Director
    No longer subject to file 2020-01-23 0

    LEVEQUE JOSEPH CHIEF MEDICAL OFFICER

    • Officer
    No longer subject to file 2020-01-23 0

    REARDON TIGHE ACTING CHIEF FINANCIAL OFFICER

    • Officer
    No longer subject to file 2020-01-23 0

    MILLA MARCOS CHIEF SCIENTIFIC OFFICER

    • Officer
    No longer subject to file 2020-01-23 0

    AVALON VENTURES X, L.P.

    AVALON X SPV, L.P.

    • 10% Owner
    No longer subject to file 2020-01-14 0

    ROMESBERG FLOYD

    • Director
    0 2019-06-07 0

    ORBIMED ADVISORS LLC

    ORBIMED CAPITAL GP VII LLC

    • Director
    • 10% Owner
    5,316,355 2018-12-11 0

    RA CAPITAL MANAGEMENT, LLC

    RA CAPITAL HEALTHCARE FUND LP

    • 10% Owner
    16,428,976 2018-12-11 0

    Insider Transactions Last 60 Days

    Reporting Owners Filing Date Trans Date Trans Code Shares Share Price Acquired
    Disposed
    Shares Owned after D/I 10b5 Perf 1d* Perf 5d* Perf 1m* Max Gain Max Gain Days Max Loss Max Loss Days
    No current insider transactions

    * -

    Transaction Code Definitions
    Code Definition
    A Grant, award or other acquisition pursuant to Rule 16b-3(d)
    C Conversion of derivative security
    D Disposition to the issuer of issuer equity securities pursuant to Rule 16b-3(e)
    E Expiration of short derivative position
    F Payment of exercise price or tax liability by delivering or withholding securities incident to the receipt, exercise or vesting of a security issued in accordance with Rule 16b-3
    G Bona fide gift
    H Expiration (or cancellation) of long derivative position with value received
    I Discretionary transaction in accordance with Rule 16b-3(f) resulting in acquisition or disposition of issuer securities
    J Other acquisition or disposition
    L Small acquisition under Rule 16a-6
    M Exercise or conversion of derivative security exempted pursuant to Rule 16b-3
    O Exercise of out-of-the-money derivative security
    P Open market or private purchase of non-derivative or derivative security
    S Open market or private sale of non-derivative or derivative security
    U Disposition pursuant to a tender of shares in a change of control transaction
    W Acquisition or disposition by will or the laws of descent and distribution
    X Exercise of in-the-money or at-the-money derivative security
    Z Deposit into or withdrawal from voting trust

    IBR Securities Loan Availability

    Updated throughout the day, this shows the number of shares available to borrow. Data provided by Interactive Brokers

    Security Date/Time Rebate Rate Fee Rate Shares Available

    Current Active Short Positions

    Holder Issuer Net Short Position Position Date Origin

    No recent transactions

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